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Pulmonary Hypertension in Hypersensitivity Pneumonitis

Recognition of Pulmonary Hypertension in Patients With Hypersensitivity Pneumonitis

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03030807
Enrollment
426
Registered
2017-01-25
Start date
2016-10-31
Completion date
2020-10-31
Last updated
2020-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Hypertension

Brief summary

The investigation serves the identification of pulmonary hypertension (PH) among patients with hypersensitivity pneumonitis (HP). The exact prevalence of PH in HP is unknown. Data from South America indicate that the prevalence of pre-capillary PH amongst patients with HP is higher than 20%. There are no reliable data from Europe so far. According to the investigators previous analysis, more than 400 HP patients have participated in pulmonary rehabilitation at least once in the past 10 years at Klinikum Bad Gleichenberg (Rehabilitation Center for Agricultural Workers in Austria). This collective of patients is to be invited to participate in the study. A diagnostic algorithm will be applied in the clinical trial, in the case of clinical suspicion the diagnosis of PH will be confirmed by right heart catheterization. Besides the determination of the prevalence of PH in patients with HP the investigators aim to assess the reliability of non-invasive methods (e.g. Echocardiography, ECG...) to predict PH.

Interventions

DIAGNOSTIC_TESTRight heart catheterization (in case of suspected PH)

Sponsors

Ludwig Boltzmann Institute for Lung Vascular Research
CollaboratorOTHER
Medical University of Graz
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No

Inclusion criteria

* Patients with confirmed Hypersensitivity Pneumonitis * written consent * Age: 18-90 years

Exclusion criteria

* severe impairment of the general health condition * pregnancy

Design outcomes

Primary

MeasureTime frame
Prevalence of pulmonary hypertension4 year

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026