Chronic Dizziness
Conditions
Keywords
chronic dizziness, persistent postural-perceptual dizziness, acceptance and commitment therapy, behavior therapy, vestibular rehabilitation
Brief summary
The purpose of this study is to examine the effectiveness of group acceptance and commitment therapy with vestibular rehabilitation for chronic dizziness, in comparison with self-treatment vestibular rehabilitation in addition to clinical management.
Detailed description
The purpose of this study is to examine whether group acceptance and commitment therapy combined with vestibular rehabilitation in addition to clinical management for patients with persistent postural-perceptual dizziness is more effective than treatment-as-usual(TAU), which is self-treatment vestibular rehabilitation in addition to clinical management.
Interventions
BEHAVIORALACT with VR
6 weekly 120-minute group sessions of acceptance and commitment therapy with vestibular rehabilitation, and brief (approximately 15 minute) individual follow-up sessions at 1 and 3 months after the group treatment
BEHAVIORALself-treatment VR
booklet written on vestibular rehabilitation for self-treatment
OTHERclinical management
clinical management and pharmacotherapy as usual for chronic dizziness
Sponsors
Nagoya City University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Masking description
Statisticians are blinded.
Eligibility
Sex/Gender
ALL
Age
20 Years to 64 Years
Healthy volunteers
No
Inclusion criteria
* Persistent postural-perceptual dizziness (diagnosed by the diagnostic guideline of ICD-11 beta version at Dec. 2016) * Existing handicap due to dizziness (DHI equal to or more than 16) * Written consent
Exclusion criteria
* Vertigo/dizziness/unsteadiness by organic brain diseases, diagnosed by neuro-otologist * Vertigo/dizziness/unsteadiness explained by only organic cause or drug, diagnosed by neuro-otologist * Physical status inappropriate for psychotherapy or vestibular rehabilitation * Current psychiatric disorder other than anxiety disorders, somatic symptom disorder, or illness anxiety disorder (DSM-5), diagnosed by psychiatrist * History of schizophrenia or bipolar disorder diagnosed by psychiatrist * Increased risk of suicide or self-harm diagnosed by psychiatrist * Started or increased SSRI/Venlafaxine within 1 month before treatment * Any cognitive behavioral therapy or vestibular rehabilitation except this study * Otological surgery or device therapy for dizziness * Insufficient understanding of the Japanese language
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Handicap due to dizziness | Post-treatment and 1, 3, and 6 months after treatment (The time point of primary interest is 3 months after treatment.) | The total score of Dizziness Handicap Inventory (DHI) (The DHI scores range from 0 to 100 points. The higher the score, the greater the handicap.) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Remission | Post-treatment and 1, 3, and 6 months after treatment | The total score of DHI equal to or less than 14 |
| Frequency of dizziness-related symptoms | Post-treatment and 1, 3, and 6 months after treatment | The total score of Vertigo Symptom Scale-short form (VSS-sf) (The VSS-sf scores range from 0 to 60 points. The higher the score, the worse.) |
| Anxiety | Post-treatment and 1, 3, and 6 months after treatment | The anxiety subscale score of Hospital Anxiety and Depression Scale (HADS) (The HADS-anxiety scores range from 0 to 21 points. The higher the score, the worse.) |
| Depression | Post-treatment and 1, 3, and 6 months after treatment | The depression subscale score of HADS (The HADS-depression scores range from 0 to 21 points. The higher the score, the worse.) |
| Response | Post-treatment and 1, 3, and 6 months after treatment | Decrease in the total score of DHI equal to or more than 11 |
| Health-related quality of life | Post-treatment and 1, 3, and 6 months after treatment | The score of EuroQOL 5 dimensions 5-level (EQ-5D-5L) (The EQ-5D-5L scores range from 0 to 1. The higher the score, the better.) |
| Valued living (progress, obstruction) | Post-treatment and 1, 3, and 6 months after treatment | The each subscale score of Valuing Questionnaire (VQ) (The scores for both VQ-progress and VQ-obstruction range from 0 to 30. The higher the VQ-progress score, the better; the higher the VQ-obstruction score, the worse.) |
| Cognitive fusion | Post-treatment and 1, 3, and 6 months after treatment | The total score of Cognitive Fusion Questionnaire (CFQ) (The CFQ scores range from 7 to 49 points. The higher the score, the worse.) |
| Somatic symptom burden | Post-treatment and 1, 3, and 6 months after treatment | The total score of Somatic Symptom Scale-8 (SSS-8) (The SSS-8 scores range from 0 to 32. The higher the score, the worse.) |
| Recovery process | Post-treatment and 1, 3, and 6 months after treatment | The total score of Recovery Assessment Scale (RAS) (The RAS scores range from 24 to 120 points. The higher the score, the better.) |
Countries
Japan
Outcome results
None listed