Sport, Supplementation, Supplements
Conditions
Keywords
β-hydroxy-β-methylbutyric acid, Sport supplements, Training support, Adaptation
Brief summary
The purpose of this study was to verify the effect of 12-week with β-hydroxy-β-methylbutyrate (HMB) and a placebo (PLA) supplementation on body composition, anaerobic and aerobic capacity, as well as concentrations of the selected biochemical blood markers in trained athletes, in a randomised, double-blind, placebo-controlled crossover trial.
Detailed description
The effect of HMB supplementation is of great interest in sport. In view of the inconclusive character of the results of the studies conducted to date and of a relatively low number of studies investigating the effectiveness of HMB supplementation over a longer period on a large population of trained athletes, the aim of this study was to verify the effect of 12-week with HMB and a placebo supplementation on body composition, anaerobic and aerobic capacity, as well as concentrations of the selected biochemical blood markers in trained athletes, in a randomised, double-blind, placebo-controlled crossover trial.
Interventions
DIETARY_SUPPLEMENTβ-hydroxy-β-methylbutyrate and a placebo supplementation
Sponsors
Poznan University of Life Sciences
National Science Centre, Poland
Poznan University of Medical Sciences
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
MALE
Age
17 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* written consent to participate, * male * a current medical clearance to practice sports, * training experience: at least 5 years, * minimum of 6 workout sessions a week (minimum 3 in the practiced sports discipline).
Exclusion criteria
* current injury, * any health-related contraindication, * declared general feeling of being unwell, * unwilling to follow the study protocol.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes of testosterone, cortisol and lactate levels in blood after placebo treatment | Baseline and after 12 weeks | — |
| Changes of anaerobic capacity after placebo treatment | Baseline and after 12 weeks | — |
| Changes of creatine kinase and lactate dehydrogenase activity in blood after HMB supplementation | Baseline and after 12 weeks | — |
| Changes of creatine kinase and lactate dehydrogenase activity in blood after placebo treatment | Baseline and after 12 weeks | — |
| Changes of testosterone, cortisol and lactate levels in blood after HMB supplementation | Baseline and after 12 weeks | — |
| Changes of body composition indices after HMB supplementation | Baseline and after 12 weeks | Analysis of the fat mass and fat free mass |
| Changes of body composition indices after placebo treatment | Baseline and after 12 weeks | Analysis of the fat mass and fat free mass |
| Changes of aerobic capacity after HMB supplementation | Baseline and after 12 weeks | — |
| Changes of aerobic capacity after placebo treatment | Baseline and after 12 weeks | — |
| Changes of anaerobic capacity after HMB supplementation | Baseline and after 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Statistical evaluation of the significance of differences between the changes in aerobic capacity indices | 1 year |
| Statistical evaluation of the significance of differences between the changes in body composition (fat mass and fat free mass) | 1 year |
| Statistical evaluation of the significance of differences between the changes in creatine kinase and lactate dehydrogenase activity and testosterone, cortisol and lactate levels in blood | 1 year |
| Statistical evaluation of the significance of differences between the changes in anaerobic capacity indices | 1 year |
Countries
Poland
Outcome results
None listed