Eclampsia, Pre-Eclampsia
Conditions
Keywords
Pre-eclampsia, Eclampsia, Postpartum uterine curettage
Brief summary
Use of Postpartum uterine curettage in reducing hospitalization time or in improving the clinical evolution of the patient with preeclampsia/eclampsia.
Detailed description
To evaluate if postpartum uterine curettage improved the clinical and laboratory parameters in patients with preeclampsia or eclampsia. A total of 442 patients with preeclampsia/eclampsia were randomized to postpartum curettage (223) or no procedure (219). Systolic and diastolic blood pressure were recorded and analyzed at hours 6, 12, 24 and 48. Also, several laboratory values and diuresis were evaluated.
Interventions
PROCEDURECurettage
Postpartum uterine curettage with a sharp curette # 14 or #16, immediately after delivery of the placenta.
PROCEDUREPlacebo
No procedure after delivery of the placenta
Sponsors
Saint Thomas Hospital, Panama
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
15 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* Gestational age 24 weeks or more. * Preeclampsia/eclampsia
Exclusion criteria
* Epilepsy or seizures previous to pregnancy. * Renal disease * Heart disease * Liver disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Systolic and diastolic blood pressure | 6 hours | Arterial blood pressure |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Laboratory results (hypertensive disorder profile: hemoglobin, hematocrit, platelets, renal or liver function tests). | 6 hours | Number of patients with an abnormal laboratory value |
| Seizures | 48 hours | Number of participants with the development of seizures after birth. |
Countries
Panama
Outcome results
None listed