Hepatitis B, HIV, Sickle Cell Disease
Conditions
Keywords
Mobile health technology
Brief summary
The investigators propose to adopt sustainable community networks (in this case churches) to implement an integrated community-based screening that incorporates mobile health technology (mHealth) to make prenatal test results available at the point-of-delivery to guide medical management.
Detailed description
The investigators will develop and test the feasibility, acceptability, and usability of a mobile health platform that captures results for HIV, Hepatitis B virus (HBV) and sickle cell genotype obtained from participants during the Healthy Beginning Initiative (HBI) program; store data in a secure, web-based database; encrypt data on a smart card which is given to participants, and make these data available at the point-of-delivery using a cell-phone application to read the smart card. Data on the web-based database can also be accessed directly using the cell phone application. Evidence exists that when clinician have maternal records available at the point of delivery, they are more likely to initiate antiretroviral prophylaxis for HIV-exposed infants, administer the first dose of hepatitis B vaccine with 24 hours for infants born to women who have positive hepatitis B surface antigen and screen infants born to mothers with sickle cell trait to allow early identification and initiation of penicillin prophylaxis for infants who have sickle cell disease.
Interventions
OTHERmHealth
HBI participants who consent will be enrolled in this study and will have data collected from their community screening stored in a secure, web-based database. The stored data will be encrypted into a Quick Response code embedded in a smart card. A unique identification number and participant's blood group type will be on the outside of the card. There will be no names or any other identifiers. Each participating center will identify a dedicated delivery room staff that will be trained to read the contents of the card using the cell phone application as well as enter new data in the participant's profile. When a participant presents at delivery without the card, information can still be obtained from the secure, web-based database and confirmed using the participant's name, date of birth and cell phone number. This information is provided to the clinician to guide management of the infant.
Sponsors
Fogarty International Center of the National Institute of Health
University of Nevada, Las Vegas
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Pregnant women; 18 years or older enrolled in the Healthy Beginning Initiative * One of the three conditions - HIV, Hepatitis B, and Sickle cell trait/disease
Exclusion criteria
* Those who do not accept to have their information uploaded on the secure database
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Reach | 6 months | Reach will be calculated as: the proportion of enrolled pregnant women relative to eligible pregnant women in the study catchment area. |
| Effectiveness | 6 months | Effectiveness will be determined by assessing the impact of the mHealth platform on key outcomes such as screening for HIV, HBV, and sickle cell genotype, and health care utilizations for follow up visits. This will be measured by calculating the percentage of pregnant women that used the smart card at the point-of-delivery. |
| Adoption | 6 months | Adoption rates will be calculated using the proportion of interested health care settings to the total number eligible for participation. |
| Acceptability | 6 months | The proportion of enrolled pregnant women who accept to use the smart card for their health care services |
Countries
Nigeria
Contacts
Primary ContactEchezona Ezeanolue, MD, MPH
Backup ContactSemiu O Gbadamosi, MD, MPH
Outcome results
None listed