Blood Flow Change After Free Flap Surgery in Diabetic Patients

Prospective Observational Study of the Changes of Blood Flow of Arterial Anastomosis-site of Free Flap in Diabetic Patients Who Undergoing Free Flap Transfer

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03027219

Enrollment

Registered

2017-01-23

Start date

2017-01-31

Completion date

2018-11-29

Last updated

2018-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes

Brief summary

We aim to evaluate the flow change of arterial anastomosis site during free flap surgery in diabetic patients.

Detailed description

Objective: flow change of arterial anastomosis site during free flap surgery in diabetic patients. Background: No research was published about flow change of arterial anastomosis site of the free flap during surgery. Plan: Using Duplex sonography, various parameters related flap perfusion will be evaluated before and after the administration of alprostadil.

Interventions

DRUGAlprostadil

Vasodilator for anastomosis-site of free flap

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 79 Years

Healthy volunteers

Inclusion criteria

1. Plan to receive free flap transfer under general anesthesia 2. Age: \>=18 and \<80 years old 3. History of diabetes mellitus 4. Administration of alprostadil during surgery 5. Volunteer, who are provided written informed consent prior to study participation

Exclusion criteria

1. Refuse the participation of study 2. \>= American society of anesthesiologist physical status IV 3. Use of any vasopressor or inotropic for hemodynamic instability before participation of study 4. Inappropriate subjects who are identified by researchers

Design outcomes

Primary

Measure	Time frame	Description
Flow change	before alprostadil administration, 30 mins after alprostadil administration	Peak velocity of anastomosis-site of free flap

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026