Cognitive Impairment, Mild, Quality of Life
Conditions
Brief summary
An observational study will be conducted in the ICU (Intensive care unit) including patients with heart surgery (\< 5 days) and prolonged ICU stay (\> 5 days). Patients will receive 5 min Virtual reality stimulation per day. A modified version of the Oculus Rift VR glasses (Facebook inc., USA) with stereoscopic vision and stereo sound will be used to present the virtual world to patients. An integrated eye tracker will measure oculomotor responses that will be synchronized with the physiological data recording. All participants will undergo neuropsychological testing after ICU stay, and after a three-months follow-up. Quality of life prior to the ICU stay will be enquired from relatives. Main outcome variable is the explorative behaviour (attention). Secondary outcomes are the quality of life and cognitive functioning.
Interventions
OTHERVisuo-acoustic stimulation
Controlled visual and acoustic stimulation in a virtual reality setting
Sponsors
University of Bern
Insel Gruppe AG, University Hospital Bern
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Age \> =18 * Speak German or French * Are able to participate the follow up measurements * Written informed consent
Exclusion criteria
* Visual impairments * Cognitive impairments * Cognitive impairments * Craniocerebral injury before admitting the ICU * Already admitted the intensive care unit (last year) or at reentry * Psychotic disorders
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Attention measurement in patients in the intensive care unit | Changes from baseline in attention measurement during and after admission (3 Month) to the ICU | The attention is measured via explorative behaviour of the subject. This means an eye tracker is used to measure eye movements, fixation duration and number of fixations, which can be used to calculate the explorative behaviour. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Quality of Life | After 3 months after admission to the ICU | The quality of life are examined via EuroQol (EQ-5D-5L) questionnaire |
| Cognitive functioning | Changes from baseline in cognitive functioning measurement after admission (3 Month) to the ICU | The cognitive abilities are examined via CERAD test battery (Consortium to Establish a Registry for Alzheimer's Disease) this includes word fluidity, Boston Naming Test (BNT), mini-mental state examination (MMSE), word list memory, constructive practice, word list retrieve, word list recognition, constructive practice (retrieve) |
Countries
Switzerland
Outcome results
None listed