Fluid Oriented Therapy During Major Abdominal Surgery

Effect Of Stroke Volume Optimization On Complication Rate Of Patients Undergoing Pancreatic Surgery

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03023618

Enrollment

180

Registered

2017-01-18

Start date

2012-01-31

Completion date

2016-05-31

Last updated

2017-01-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Goal Directed Therapy

Keywords

[G09.330.380]

Brief summary

In this before and after study we will investigate the potential benefit on postoperative outcomes of a guided fluid therapy with a stroke volume optimization . The NICE protocol has been applied by means of EV1000 monitor and arterial waveform analysis ( Flotrac - Edwards). In the postoperative period overall complications, as well as exitus , will be analyzed and compared with those of a control group underwent the same surgical interventions, with a standard hemodynamic monitoring.

Interventions

DEVICEFloTrac

Stroke Volume has been maintained at 90% of the maximal Stroke Volume as in NICE protocol 2011

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* ASA 1-2 patients

Exclusion criteria

* Severe Caridiac Disease * Renal Failure

Design outcomes

Primary

Measure	Time frame
complication rate	up to 30 days postoperatively

Secondary

Measure	Time frame
Duration of hospitalization	an average of 30 days

Other

Measure	Time frame
amount of intraoperative fluids	an average of 12 hours

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026