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UWCCC Molecular Tumor Board Registry

UWCCC Precision Medicine Molecular Tumor Board Registry

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03023202
Enrollment
10000
Registered
2017-01-18
Start date
2016-03-30
Completion date
2029-03-01
Last updated
2026-04-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hematologic Neoplasms, Solid Neoplasm

Brief summary

This study seeks to evaluate the clinical utility of the Precision Medicine Molecular Tumor Board, and to track patient outcomes.

Interventions

OTHERPMMTB (Precision Medicine Molecular Tumor Board)

PMMTB is a clinical intervention, NOT a research intervention. The research component of this study is to observe the outcomes of the PMMTB.

Sponsors

University of Wisconsin, Madison
Lead SponsorOTHER
National Cancer Institute (NCI)
CollaboratorNIH

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Clinically suspected or histologically confirmed solid or hematological malignancy * Undergoing genetic testing of tumor * Ability to understand written informed consent document * Willingness to sign written informed consent document

Exclusion criteria

* Pediatric patients (age\<18 years) will be excluded due to a lack of expertise on the molecular tumor committee

Design outcomes

Primary

MeasureTime frameDescription
Frequency of acceptance of molecular tumor board recommendationsUp to 5 yearsHow often the molecular tumor board's recommendations are accepted
Benefit from PMMTB recommended treatmentUp to 5 yearsWhether patients benefit from PMMTB recommended treatment

Secondary

MeasureTime frameDescription
Correlation of mutations with protein overexpressionUp to 5 yearsCorrelate mutations identified in tumor tissue with protein overexpression
Correlations of mutations with circulating tumor DNAUp to 5 yearsCorrelate mutations identified in tumor tissue with circulating tumor DNA
Correlations of mutations with spheroid culture investigationsUp to 5 yearsCorrelate mutations identified in tumor tissue with spheroid culture investigations

Countries

United States

Contacts

CONTACTCancer Connect
clinicaltrials@cancer.wisc.edu8006228922
PRINCIPAL_INVESTIGATORDustin Deming, MD

University of Wisconsin, Madison

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 14, 2026