Coronary Heart Disease
Conditions
Keywords
mobile health, veterans, cardiovascular disease, medication adherence
Brief summary
The purpose of this study is to determine whether text messages/messaging (TM) or a mobile application (app), compared with an educational website-control provided to all Veterans, can improve adherence to antiplatelet therapy among patients following acute coronary syndrome or percutaneous coronary intervention (ACS/PCI).
Detailed description
Adherence to antiplatelet medications is critical to prevent life threatening complications (i.e., stent thrombosis); yet rates of non-adherence range from 21-57% by 12 months. Mobile technology through TM or mobile apps is a practical and inexpensive strategy to promote behavior change and enhance medication adherence. The three specific aims of this proposal are to: 1) determine preferences for content and frequency of TM to promote medication adherence through focus groups; 2) determine the most patient-centered app to promote adherence through a content analysis of all commercially available apps for medication adherence and focus groups centered on usability; and 3) compare adherence to antiplatelet medications in 225 Veterans post ACS/PCI through a randomized controlled trial. Participants will be randomized to either TM, mobile app, or website-control group. The focus groups will be stratified by low/high mobile phone use and sex.
Interventions
BEHAVIORALText Message
Annie (VA text messaging program) or mobile Health manager (private text messaging program for non-VA female participants recruited at non-VA facility)
BEHAVIORALMobile Application
OTHERWebsite
American Heart Association patient education website
Sponsors
John Muir Medical Center
North Florida/South Georgia Veterans Health System
North Texas Veterans Healthcare System
VA Palo Alto Health Care System
San Francisco Veterans Affairs Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
21 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* ≥ 21 years of age, * recent ACS or PCI within 1 week * new antiplatelet (thienopyridine) prescription * owns a smartphone
Exclusion criteria
* cognitive impairment * lack of English proficiency/literacy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in medication adherence over 12 months | 12 months | Medication Event Monitoring System (MEMS) which is an electronic pill bottle cap that captures medication taking patterns |
| Change in medication adherence at 12 months | 12 months | Medication recall questionnaire that will assess how many missed doses there were. |
Countries
United States
Contacts
Primary ContactLinda Park, PhD, MS, FNP
Backup ContactJulia von Oppenfeld
Outcome results
None listed