Assessment of a Pre-Workout Supplement

Pharmacokinetic, Hemodynamic and Ergogenic Assessment of a Pre-Workout Dietary Supplement

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03022604

Acronym

NB6

Enrollment

Registered

2017-01-16

Start date

2015-06-30

Completion date

2015-09-30

Last updated

2017-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exercise Ergogenics

Brief summary

This study is assessing the effects of a pre-workout dietary supplement.

Detailed description

The purpose of this study is to examine the acute effects of a pre-workout dietary supplement at a standard dose and one that is delivered at 150% of the standard dose on energy metabolism, cardiovascular hemodynamics, blood metabolites and mental focus.

Interventions

DIETARY_SUPPLEMENTC4/Generation 4

12 grams of C4/Generation 4

DIETARY_SUPPLEMENTC450X

12 grams of C450X

DIETARY_SUPPLEMENTPlacebo

12 grams of flavored dextrose

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

HEALTH_SERVICES_RESEARCH

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* Participants must be apparently healthy males and/or females between the ages of 18 and 40 * Participants must have at least 6 months immediate prior history of resistance training including the bench press and leg press/squat

Exclusion criteria

* Participants who have a history of treatment for metabolic disease (i.e., diabetes), hypertension, hypotension, thyroid disease, arrhythmias and/or cardiovascular disease * Participants who currently use any prescription medication * Participants who are intolerant to caffeine and/or other natural stimulants * Participants who are pregnant or lactating women * Participants who have a history of smoking * Participants who drink excessively (12 drinks per week)

Design outcomes

Primary

Measure	Time frame
Effects of a Pre-Workout Dietary Supplement on total work on the leg press	Seven Days
Effects of a Pre-Workout Dietary Supplement on VAS Readiness to Perform	Seven Days
Effects of a Pre-Workout Dietary Supplement on anaerobic sprint capacity on a bicycle ergometer	Seven Days
Effects of a Pre-Workout Dietary Supplement on bench press power output	Seven Days
Effects of a Pre-Workout Dietary Supplement on leg press power output	Seven Days
Effects of a Pre-Workout Dietary Supplement on total work on the bench press	Seven Days
Effects of a Pre-Workout Dietary Supplement on the Stroop Color and Word Test	Seven Days
Effects of a Pre-Workout Dietary Supplement on the Word Recall Test	Seven Days

Secondary

Measure	Time frame
Effects of a Pre-Workout Dietary Supplement on heart rate	Seven Days
Effects of a Pre-Workout Dietary Supplement on blood pressure	Seven Days
Effects of a Pre-Workout Dietary Supplement on ECG's	Seven Days
Effects of a Pre-Workout Dietary Supplement on blood lab results	Seven Days
Effects of a Pre-Workout Dietary Supplement on energy expenditure	Seven Days

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026