Prediction of Postoperative Pain by Injection Pain of Propofol

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03021447

Enrollment

Registered

2017-01-16

Start date

2017-01-31

Completion date

2017-12-31

Last updated

2017-01-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholecystitis, Acute

Brief summary

Postoperative pain is a significant postoperative problem and it could be persistent if proper management is not provided. However, each patient shows different intensity of pain and different sensitivity to analgesics even if they underwent same procedures. Therefore, it would be useful to find the way to predict the postoperative pain sensitivity. Propofol, a popular anesthetic agent, induces pain during injection, which can not completely prevented by opioid or lidocaine in some patients. This is considered to be related to patient's pain sensitivity and it might be associated with postoperative pain sensitivity. Therefore, the relation of propofol injection pain and postoperative pain intensity will be explored.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

19 Years to 60 Years

Healthy volunteers

Inclusion criteria

* America Society of Anesthesiologists class I-II * Laparoscopic cholecystectomy

Exclusion criteria

* Pregnancy * Illiteracy

Design outcomes

Primary

Measure	Time frame	Description
postoperative pain intensity_1	10 min after postanesthesia care unit admission	Postoperative pain will be evaluated with verbal numeric scale (0-10)

Secondary

Measure	Time frame	Description
postoperative pain intensity_2	20 min after postanesthesia care unit admission	Postoperative pain will be evaluated with verbal numeric scale (0-10)
postoperative pain intensity_3	30 min after postanesthesia care unit admission	Postoperative pain will be evaluated with verbal numeric scale (0-10)
postoperative pain intensity_4	4 hours after operation	Postoperative pain will be evaluated with verbal numeric scale (0-10)
postoperative pain intensity_8	8 hours after operation	Postoperative pain will be evaluated with verbal numeric scale (0-10)
postoperative pain intensity_12	12 hours after operation	Postoperative pain will be evaluated with verbal numeric scale (0-10)
postoperative pain intensity_24	24 hours after operation	Postoperative pain will be evaluated with verbal numeric scale (0-10)

Outcome results