Predictors of Hypofibrinogenemia in Severe Trauma

Can we Define a Clinical Score for Predicting of Hypofibrinogenemia in Severe Trauma

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03020849

Enrollment

1038

Registered

2017-01-13

Start date

2011-01-31

Completion date

2015-03-31

Last updated

2017-07-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe Trauma

Keywords

hypofibrinogenemia, prediction score, severe trauma

Brief summary

In this retrospective and prospective study, the aim is to determine a score for predicting a fibrinogen \<1.5g/L (corresponding to European threshold of Directors recommendations of fibrinogen concentrates)

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* age \> 18 * severe trauma

Exclusion criteria

* age \<18

Design outcomes

Primary

Measure	Time frame	Description
rate of fibrinogen in blood sample at hospitalisation	day 0 (at hospitalisation)	This fibrinogen rate is correlated to pre-hospital and admission clinical parameters (trauma type, physiologic status, treatments administered, biologic checkup) to predict fibrinogenemia at hospitalisation

Countries

France

Outcome results