Effect of Red Meat Intake on Occurrence of Serum Non-transferrin Bound Iron (NTBI)

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03019393

Enrollment

Registered

2017-01-12

Start date

2016-05-31

Completion date

2017-03-31

Last updated

2017-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

non-transferrin bound iron (NTBI), Red meat, Non-transferrin bound iron (NTBI) in serum

Brief summary

This study aims to evaluate the effect of red meat intake on occurrence of non-transferrin bound iron (NTBI)

Detailed description

During Visit 1, blood samples will be collected to assess iron status. During Visit 2, after an overnight fast, participant will be given a standardized meal (rice and potatoes) with a portion of cooked beef (200 g). Blood samples will be collected right before and 2 hour after the meal for NTBI analysis. NTBI concentration before and after meal consumption will be compared.

Interventions

OTHERBeef

200 g beef topside which is fully cooked will be provided to participant after overnight fast. The intervention is one time only.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

MALE

Age

21 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

* Apparently healthy male volunteers (21 - 45 years old) * C-reactive protein (CRP) \< 5 mg/L

Exclusion criteria

* Blood donation or significant blood loss (e.g. surgery) within the past 4 months * Regular intake of iron and other nutrient supplements within the past 4 months * Regular intake of medication except oral contraceptives * Acute or recent inflammatory or infectious symptoms * Chronic gastrointestinal disorders or metabolic diseases * Smoking * Coeliac disease or gluten-related disorders * Iron deficiency anemia (Hb \< 14 g/dL for males) with serum ferritin concentration \< 30 ng/mL) * Non-iron deficiency anemia (serum ferritin concentration within normal range (30 - 300 ng/mL for males) but low hemoglobin (\< 14 g/dL for males) * Iron overload conditions (serum ferritin concentration \> 300 ng/mL for males) * Known hereditary disorders of iron metabolism

Design outcomes

Primary

Measure	Time frame	Description
Occurrence of serum non-transferrin bound iron (NTBI) after consumption of red meat	2 hour post meal administration	Blood samples collected 2 h after consumption of red meat will be analyzed for non-transferrin bound iron (NTBI) concentration

Countries

Singapore

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026