Change in Breathing Pattern on Non-invasive Ventilation of COPD Patients Under Home Mechanical Ventilation

Usefulness of built-in Non-invasive Ventilator Software to Detect the Change in the Breathing Pattern of COPD Patients Under Home Mechanical Ventilation Before an Admission for Acute Exacerbation of COPD.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03018470

Enrollment

Registered

2017-01-12

Start date

2017-01-31

Completion date

2017-08-31

Last updated

2018-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Copd, COPD Exacerbation

Keywords

COPD, Non invasive ventilation, NIV, Acute exacerbation COPD, AECOPD, Telemonitoring

Brief summary

Acute exacerbation of COPD (AECOPD) worsen prognosis and quality of life of COPD patients. Telemonitoring could be a useful tool for early identification of AECOPD. Parameters that have to be monitored are not well defined. Patients with severe COPD may use home non-invasive ventilation (NIV). NIV have built-in software which are recording the breathing pattern of patients when used. The aim of this study is to identify ventilation parameters that are modified at the early stage of an AECOPD.

Interventions

OTHERAnalysis of data from NIV built-in software

Analysis of breathing pattern using data obtained from NIV built-in software

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Diagnosed COPD according to GOLD guidelines * Established on home non invasive ventilation for more than 2 weeks

Exclusion criteria

* None

Design outcomes

Primary

Measure	Time frame
Change of respiratory rate at the early onset of AECOPD	10 days

Secondary

Measure	Time frame
Correlation between the length of the change in the breathing pattern under NIV and the length of inpatient stay	10 days
Correlation between the importance of the change in the breathing pattern under NIV and the severity of the AECOPD	10 days
Change of tidal volume at the early onset of AECOPD	10 days
Change of leaks at the early onset of AECOPD	10 days
Change of length of use of NIV at the early onset of AECOPD	10 days
Correlation between the change in symptoms and in the breathing pattern under NIV	10 days
Change of proportion of triggered breaths during the use of NIV at the early onset of AECOPD	10 days
Change of proportion of asynchronisms during the use of NIV at the early onset of AECOPD	10 days
Change of the number of residual respiratory events during the use of NIV at the early onset of AECOPD	10 days
Change of the inspiratory time during the use of NIV at the early onset of AECOPD	10 days
Sensitivity and specificity of change in the breathing pattern under NIV to detect an AECOPD	10 days
Change of number of breaks during the use of NIV at the early onset of AECOPD	10 days

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026