Myocardial Infarction
Conditions
Brief summary
Prospective cohort evaluating patients in the State of Santa Catarina (Brazil) with the diagnosis of the first acute myocardial infarction from July 2016 until December 2020.
Interventions
OTHERMyocardial Infarction
Observational study of myocardial Infarction patients
Sponsors
Instituto de Cardiologia de Santa Catarina
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age over 18 years; * Presence of precordial pain suggestive of acute myocardial infarction associated with electrocardiogram with new ST segment elevation in two contiguous leads with limits: ≥0.1 mv in all leads other than leads V2-V3 where the following limits apply : ≥0.2 mv in Men ≥40 years; ≥0.25 mV in men \<40 years, or ≥ 0.15 mV in women or presence of precordial pain suggestive of acute myocardial infarction associated with elevation of troponin I or CK-MB above the 99th percentile of the upper reference limit
Exclusion criteria
* Previous acute myocardial infarction; * Disagreement with the Terms of Informed Consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MACE in 1 year | Major cardiovascular events - MACE (cardiovascular death, nonfatal infarction, unstable angina or stroke) in 1 year |
| MACE in 30 days | Major cardiovascular events - MACE (cardiovascular death, nonfatal infarction, unstable angina or stroke) in 30 days |
| Death in 1 year | Death incidence in 1 year |
| Death in 30 days | Death incidence in 30 days |
| Restenosis in 1 year | Restenosis incidence in 1 year |
| Restenosis in 30 days | Restenosis incidence in 30 days |
| Intrastent thrombosis in 1 year | Intrastent thrombosis incidence in 30 days |
| Intrastent thrombosis in 30 days | Intrastent thrombosis incidence in 30 days |
| Cardiovascular death in 1 year | Cardiovascular death incidence in 1 year |
| Cardiovascular death in 30 days | Cardiovascular death incidence in 30 days |
| Nonfatal infarction in 1 year | Nonfatal infarction incidence in 1 year |
| Nonfatal infarction in 30 days | Nonfatal infarction incidence in 30 days |
| Unstable angina in 1 year | Unstable angina incidence in 1 year |
| Unstable angina in 30 days | Unstable angina incidence in 30 days |
| Stroke in 1 year | Stroke incidence in 1 year |
| Stroke in 30 days | Stroke incidence in 30 days |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Caffeine consumption | Caffeine consumption at admission | Caffeine consumption at admission and its correlation with other evaluated parameters and its association with death, hospitalization, stroke, acute coronary syndromes and infarction |
| Alcoholic beverages consumption | Alcoholic beverages consumption at admission | Alcoholic beverages consumption at admission and its correlation with other evaluated parameters and its association with death, hospitalization, stroke, acute coronary syndromes and infarction |
| Illegal drugs consumption | Illegal drugs consumption at admission | Illegal drugs consumption at admission and its correlation with other evaluated parameters and its association with death, hospitalization, stroke, acute coronary syndromes and infarction |
| Cognitive level | Cognitive level at admission | Cognitive level (evaluated with Mini-Mental State Examination) at admission and its correlation with other evaluated parameters and its association with death, hospitalization, stroke, acute coronary syndromes and infarction syndromes and infarction |
| Religiosity | Religiosity at admission | Religiosity (evaluated with Duke University Religion Index) at admission and its correlation with other evaluated parameters and its association with death, hospitalization, stroke, acute coronary syndromes and infarction |
| Pre-infarct physical activity | Pre-infarct physical activity at admission | Pre-infarct (evaluated with Baecke Questionnaire) physical activity at admission and its correlation with other evaluated parameters and its association with death, hospitalization, stroke, acute coronary syndromes and infarction |
| Depression | Depression at admission | Depression (evaluated with PHQ-9: Patient Health Questionnaire-9) at admission and its correlation with other evaluated parameters and its association with death, hospitalization, stroke, acute coronary syndromes and infarction |
| Syntax score | Syntax score at admission | Syntax score at admission and its correlation with other evaluated parameters and its association with death, hospitalization, stroke, acute coronary syndromes and infarction |
| TIMI frame count | TIMI frame count in patients with primary angioplasty at admission | TIMI frame count in patients with primary angioplasty at admission its correlation with other evaluated parameters and its association with death, hospitalization, stroke, acute coronary syndromes and infarction |
| Ventricular function post-infarction | Ventricular function post-infarction (evaluated within 72 hours of admission) | Ventricular function (ventricular ejection fraction), its correlation with other evaluated parameters and its association with death, hospitalization, stroke, acute coronary syndromes and infarction |
| Troponin levels | Troponin levels at admission | — |
| CHA2DS2-VASc Score | CHA2DS2-VASc Score at admission | CHA2DS2-VASc Score, its correlation with other evaluated parameters and its association with death, hospitalization, stroke, acute coronary syndromes and infarction |
| Bleeding in 1 year | Bleeding incidence in 1 year | — |
| Bleeding in 30 days | Bleeding incidence in 30 days | — |
| Hematocrit and hemoglobin | Hematocrit and hemoglobin at the admission | — |
| Hematocrit and hemoglobin in 72 hours | Hematocrit and hemoglobin in 72 hours | — |
| Cholesterol levels | Cholesterol levels at admission | — |
| C-reactive protein | C-reactive protein at admission | — |
| Red Cell Distribution Width (RDW) | Red Cell Distribution Width (RDW) at admission | — |
| Leukocytes | Leukocytes at admission | — |
| Creatinine | Creatinine at admission | — |
| Hospitalization in 1 year | Hospitalization incidence in 1 year | — |
| Hospitalization in 30 days | Hospitalization incidence in 30 days | — |
| Epidemiological profile | Epidemiological profile of hospitalized patients with infarction in Santa Catarina at the admission | — |
| Fish consumption | Fish consumption at admission | Fish consumption at admission and its correlation with other evaluated parameters and its association with death, hospitalization, stroke, acute coronary syndromes and infarction |
| Red meat consumption | Red meat consumption at admission | Read meat consumption at admission and its correlation with other evaluated parameters and its association with death, hospitalization, stroke, acute coronary syndromes and infarction |
| Chocolate consumption | Chocolate consumption at admission | Red meat consumption at admission and its correlation with other evaluated parameters and its association with death, hospitalization, stroke, acute coronary syndromes and infarction |
Countries
Brazil
Outcome results
None listed