Posterior Maxillary Ridge Augmentation With Sinus Lift Using Mineralized Plasmatic Matrix Versus Autogenous Bone Graft

Posterior Maxillary Ridge Augmentation With Sinus Lift Using Mineralized Plasmatic Matrix Versus Autogenous Bone Graft (A Randomized Clinical Trial Comparative Study)

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03014388

Acronym

MPM

Enrollment

Registered

2017-01-09

Start date

2017-01-31

Completion date

2017-10-31

Last updated

2017-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone Resorption

Brief summary

Using growth factors obtained from patient's venous blood mixed with particulate autogenous bone the study compares bone gain by implant with gold standards in sinus Lift procedures for future implant insertion.

Detailed description

To study the effectiveness of MPM in ridge augmentation with implant insertion compared with autogenous bone graft. -PICO Population(P) : Patients with defective posterior maxillary alveolar ridge. Intervention (I) :Implant placement and ridge augmentation with MPM. Comparator (C) : Autogenous bone graft. Outcome (O) : Patient satisfaction - Implant stability.

Interventions

OTHERautogenous bone

Autogenous bone graft (gold standard). sinus lift with autogenous bone.

OTHERMineralized plasmatic matrix

By using venoud blood from the patient, together with bone graft, a centrifuge will be used to obtain the top layer after centrifuging blood at 3000 RPM.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

1. Patients systemically free. 2. Patients with posterior maxillary defective ridges indicated for sinus lift procedure. 3. Cases with 5 mm bone height or less are included in the study. 4. Age between 18 and 50 years. 5. Both sexes. 6. Patients physically able to tolerate surgical and restorative procedures. 7. Good oral hygiene. 8. Highly motivated patients.

Exclusion criteria

1. Patients allergic to local anesthetic agent. 2. Medium and heavy smokers. 3. Pregnant females. 4. Presence of any pathosis in the pre-implant site. 5. Presence of any mucosal disease. 6. History of oral radiotherapy. 7. History of prolonged steroids use. 8. Psychological disorders.

Design outcomes

Primary

Measure	Time frame	Description
Patient Satisfaction regarding aesthetic results will be measured using questionnaire.	9 months	outcome will be measure using questionnaire.

Secondary

Measure	Time frame	Description
Stability of dental implants.	5 months	will be measured using OSTELL Device.

Contacts

Primary Contactrefaat ragab, Master

refaat.ragab.rr@gmail.com01111175536

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026