CTCs and Novel Target Bio-marker Analysis for Prediction and Monitoring of Metastasis/Recurrence in Post-surgery Colorectal Cancer Patients Using MiSelect R Rare Cell System

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03013868

Enrollment

200

Registered

2017-01-09

Start date

2016-10-31

Completion date

2021-02-28

Last updated

2018-08-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Circulating Tumor Cells, CTC

Brief summary

Despite the growing public awareness and recent progress in multimodality therapy to the colorectal cancer (CRC), CRC still ranks high on the list of the most common and deadly cancers in Taiwan. The cause of CRC mortality is due mainly to the occurrence of distant metastasis. Several reports suggested that circulating tumor cells (CTCs) highly associated with metastasis suggesting that targeting CTCs may offer an unprecedented opportunity to prevent the development of metastasis. Early detection and characterization of CTCs is therefore important as a potential strategy to monitor the progression of CRC. The current proposal is focused on detecting CTCs from peripheral blood of CRC patients using Miselect R system. We will monitor the amount of CTCs and correlate with CRC progression and prognosis.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to 90 Years

Healthy volunteers

Inclusion criteria

1. Over 20 and less than 90 years of age. 2. Colorectal cancer stage II/III patients who will undergo surgical resection. 3. Subject having agreed to participate in the study and follow the study procedures by providing written informed consent prior entering the study.

Exclusion criteria

1. Have other cancer history. 2. Subject being identified with any blood borne infectious disease

Design outcomes

Primary

Measure	Time frame
Disease Free Survival	5 years

Countries

Taiwan

Contacts

Primary ContactWang Henry, Master

henrywang@micareo.com886-2-2796-5096

Outcome results