Venous Congestion and Acute Renal Failure in Cardiac Surgery Postoperative

Venous Congestion and Acute Renal Failure in Cardiac Surgery Postoperative (COVD)

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03013621

Acronym

COVD

Enrollment

Registered

2017-01-06

Start date

2017-01-31

Completion date

2018-01-31

Last updated

2017-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Renal Failure (ARF)

Keywords

Renal Failure, Renal Insufficiency, Acute Renal Failure, Acute Renal Injury, Kidney Failure, Kidney Insufficiency, Acute Kidney Failure, Acute Kidney Injury, Ventricular dysfunction, Venous congestion, Renal function, Kidney function, Venous heart failure

Brief summary

Acute renal failure (ARF) is a frequent complication in the postoperative cardiac surgery, and is a major risk factor for mortality in this context. The right ventricular dysfunction post cardiopulmonary bypass (CPB) is also a common complication, close to 100% if one takes into account the transient dysfunction. A recent study showed that right ventricular dysfunction and the IRA seemed related, rather on the slope of venous congestion. We wish to study this phenomenon more specifically in particular to offer reliable diagnostic markers of venous congestion.

Interventions

None listed

Study design

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age: all major patient * Gender: both * Subject has signed an informed consent * IRA KDIGO stage 1 or urine output \<0.5 mL / kg / h for at least 6 hours / elevation creat\> 26.5μmol / L * Patient in sinus rhythm at the time of the ultrasound measurements * No diuretic since intervention * Absence of circulatory failure (low doses of catecholamines tolerated) * Extubated: absence of mechanical ventilation

Exclusion criteria

* Chronic heart failure right * Chronic renal failure (GFR \<60) * Usual treatment with high dose diuretics (furosemide\> 40mg / day) * Endocarditis * Emergency surgery (aortic dissection, emergency bypass surgery) / heart surgery D / redux * Circulatory Support * ACFA / electro-paced rhythm * Inability to give informed about information (subject in emergencies, understanding of the subject of difficulty, ...) * Topic under judicial protection * Topic guardianship or curatorship * Pregnancy (women of childbearing age) * Breastfeeding

Design outcomes

Primary

Measure	Time frame
Quantification of sonographic markers of right ventricular	1 hour after cardiac surgery

Countries

France

Contacts

Primary ContactPaul-Michel MERTES, MD, PhD

paul-michel.mertes@chru-strasbourg.fr33 3 69 55 15 78

Backup ContactMircea CRISTINAR, MD

mircea.cristinar@chru-strasbourg.fr33 3 69 55 12 65

Outcome results