Dyspnea
Conditions
Brief summary
An uncontrolled feasibility study on using mouth piece ventilation in palliation of dyspnea in subjects with incurable advanced disease. Subjects are recruited from a local Hospice and from oncology ward. The main outcomes are the compliance of the subjects with the treatment and alleviation of dyspnea during the treatment period.
Interventions
Trilogy 100 ® (Philips Respironics) on MPV mode.
Sponsors
Tampere University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* at least moderate dyspnea (NRS = Numeric Rating Scale ≥ 4) * incurable advanced disease * able to understand the study and to give informed consent * would not gain from intensive care or resuscitation according to the treating physician
Exclusion criteria
* unable to participate and use MPV due to e.g. delirium or lack of co-operation * the cause of the dyspnea can be succesfully treated * unable to give informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in dyspnea after initial use of MPV | 5 - 60 min |
Secondary
| Measure | Time frame |
|---|---|
| Change in dyspnea after 24 hours of using MPV | 24 hours |
| Proportion of subjects having side-effects or not being compliant with MPV | 24 hours |
| Proportion of subjects gaining from MPV | 24 hours |
| Proportion of subjects willing to continue on MPV after the intervention | 24 hours |
Countries
Finland
Outcome results
None listed