Trans-thoracic Ultrasound VS Invasive Pressure of the Left Atrium

Evaluation of Left Ventricular Filling Pressures in Post-operative Cardiac Surgery: Trans-thoracic Ultrasound VS Invasive Pressure of the Left Atrium

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03012308

Acronym

ECHOPOG

Enrollment

100

Registered

2017-01-06

Start date

2016-12-20

Completion date

2017-12-20

Last updated

2017-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myocardial Dysfunction

Keywords

Myocardial Dysfunction, left ventricular, mitral valve doppler, mitral ring doppler, ultrasound signs, lung edema

Brief summary

As part of cardiac and hemodynamic evaluation of patients, echocardiographic measurements allow indirect evaluation of left ventricular filling pressures (LVFP). These ultrasound parameters, including mitral valve doppler and mitral ring doppler (in particular the E / E 'ratio), are well validated in medical cardiology and in some resuscitation patients. The measurement of filling pressures is an important daily element in the medical management of patients in intensive care, in particular on the hemodynamic and respiratory levels. No studies have evaluated the relevance of these markers in a postoperative context of cardiac surgery. Indeed, the surgery alters the cardiac function, which could modify the values of the echocardiographic parameters and their predictability. Left atrium pressure (LAP) directly reflects LVFP and is measured in cardiac surgical resuscitation by a surgically placed catheter as part of routine institutional care and will serve as gold-standard. To study the clinical significance of these LAP and LVFP values estimated by cardiac ultrasound, we will study their correlation with clinical and ultrasound signs of acute lung edema (ALE).

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patient hospitalized in surgical resuscitation for cardiac surgery with heart-lung bypass machine

Exclusion criteria

* No consent * Mitral valve surgery * severe MI / severe mitral narrowing. * Absence of POG catheter * Urgent surgery * Heart transplant / mechanical assistance * Classics: minors, pregnant women, guardianship / curatorship / safeguarding,

Design outcomes

Primary

Measure	Time frame
Compare the mean values of LAP between the group high filling pressures and the group non-high filling pressures	6 postoperative hours of cardiac surgery of patients hospitalized in surgical resuscitation

Countries

France

Contacts

Primary ContactGharib AJOB, MD

gharib.ajob@chru-strasbourg.fr33 3 69 54 97 58

Backup ContactPaul-Michel MERTES, MD, PhD

paul-michel.mertes@chru-strasbourg.fr33 3 69 55 15 78

Outcome results