Does Simethicone Improve Operative Field in Gynecological Operations

Status

UNKNOWN

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03009604

Enrollment

Registered

2017-01-04

Start date

2017-01-31

Completion date

2017-05-31

Last updated

2017-01-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign Gynecologic Neoplasm

Brief summary

Mechanical bowel preparation aims to decrease the volume fecal content in the colon, which thereby decreases the total colony count of bacteria, thus, decreasing peritoneal contamination in case of bowel injury, improving the access to the surgical field and facilitating intraoperative bowel manipulation

Interventions

DRUGSimethicone

Simethicone 40mg oral tablets

DRUGEnema

sodium dihydrogen phosphate dihydrate 19.2 gram & disodium hydrogen phosphate dodecahydrate 7.2 gram, in addition to purified water

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

20 Years to 60 Years

Healthy volunteers

Inclusion criteria

Gynecological operations for benign conditions as hysterectomy, ovarian cystectomy and myomectomy.

Exclusion criteria

1. History of allergic reaction to study drugs. 2. More than one scar of previous operation. 3. Suspicious of malignancy. 4. Psychiatric disorders.

Design outcomes

Primary

Measure	Time frame
the degree of small & large bowel preparation	intraoperative

Countries

Egypt

Contacts

Primary ContactAltayeb Mostafa, MBBCh

00201003722811

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026