Fetal Pulmonary Artery Acceleration to Ejection Time Ratio (PATET) in the Prediction of Subsequent Development of Respiratory Distress Syndrome (RDS)

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03008200

Enrollment

115

Registered

2017-01-02

Start date

2015-12-31

Completion date

2016-09-30

Last updated

2017-01-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

RDS

Brief summary

Fetal PATET ratio evaluation to predict neonatal RDS

Detailed description

115 patients were enrolled in this study.Population was recruited from singleton pregnancies beyond 27 weeks of gestation.All participants underwent a ultrasound examination to measure fetal pulmonary artery acceleration to ejection time ratio (PATET) by a single experienced clinician. After the delivery respiratory distress diagnosis made by a pediatrician who were blinded the doppler waveform measurements.Following the diagnosis, neonates divided into 2 groups as RDS (+) and RDS (-). In addition of RDS diagnosis, neonatal features like 1st and 5th minute APGAR scores, neonatal intensive care unit (NICU) admission and duration in NICU were also recorded. Afterwards all parameters were statistically analyzed if there is any significant differences between those two groups.

Interventions

DEVICEultrasound examination

intrauterine fetal pulmonary artery acceleration time to ejection time ratio measurement via ultrasound

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Healthy volunteers

Yes

Inclusion criteria

* pregnant women within the 27 weeks of gestation and beyond

Exclusion criteria

* patients who did not give birth within 3 days after the ultrasonographic doppler examination * fetuses with Any congenital abnormalities * amniotic fluid abnormalities * any chronic maternal diseases or pregnancy complications such as;gestational diabetes mellitus,preeclampsia

Design outcomes

Primary

Measure	Time frame	Description
Measurement of fetal pulmonary acceleration time to ejection time ratio via ultrasonography in the 115 pregnant women between 27 to 37 weeks of gestation for prediction of respiratory distress syndrome	Ten months	The aim of this study is to obtain the effectiveness of fetal pulmonary artery acceleration time to ejection time ratio in fetal lung maturity evaluation

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026