Monitoring During Deliberate Hypotensive Anesthesia
Conditions
Brief summary
Hypotensive anesthesia is effective in reducing the intraoperative blood loss. The risk of hypoperfusion of vital organs continues to be a concern. An adequate monitoring of tissue perfusion and oxygenation is crucial issue. Peripheral Perfusion Index (PPI) as a noninvasive new monitoring, can reflect the peripheral perfusion dynamics. This study is designed to explore the behaviour and trend of PPI during nitroglycerine induced deliberate hypotensive anesthesia in adult patients undergoing functional endoscopic sinus surgery (FESS).
Interventions
OTHERperipheral perfusion index measurement
Sponsors
Cairo University
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* Patients, aged from 18-50 years, ASA physical status I and II, undergoing functional endoscopic sinus surgery (FESS) under deliberate hypotensive anesthesia
Exclusion criteria
* Patients with systemic hypertension, cardiovascular disease, cerebrovascular insufficiency, coagulation defects, renal or hepatic insufficiency, and hypersensitivity to the study drugs will be excluded from the study. Patients receiving vasoactive drugs or beta blockers will be also excluded from the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| correlation between PPI and T1 | start of nitroglyceirn infusion till target arterial pressure is reached up to 2 hours | correlation of baseline values of PPI and time required to achieve target mean arterial pressure. |
Outcome results
None listed