Oxygen Deficiencies, Smoking
Conditions
Keywords
secondary smoking, one lung ventilation, arterial oxygen tension, lobectomy
Brief summary
Smoking and perhaps secondary smoking is associated with many perioperative and postoperative complications, especially respiratory events. Hypoxemia and airway damage can be associated with secondary smoking. The aim of study is to predict the incidence of hypoxemia and airway damage during one lung ventilation for lobectomy.
Detailed description
Sixty patients undergoing lobectomy using one lung ventilation by double lumen tube will be included in this study. These patients will be divided into 2 groups. Groups S which will be included non smoking and secondary smoking and group SS which will be included secondary smoking ( smoking near him more than 10 cigarettes per day fore more than 5 years). Intra and postoperative arterial oxygen tension, arterial carbon dioxide tension and intraoperative peak airway pressure will be compared between the two groups.
Interventions
OTHEROne Lung Ventilation
Sponsors
Inonu University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Investigator)
Eligibility
Healthy volunteers
No
Inclusion criteria
* Sixty patients undergoing lobectomy using one lung ventilation by double lumen tube, ASA physical status 2 and 3.
Exclusion criteria
* Recent chest infection, morbid obesity, renal, hepatic and ischemic hearts disease, asthma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| arterial oxygen tension | From beginning of Anesthesia to 1st day of surgery |
| arterial carbon dioxide tension | From beginning of Anesthesia to 1st day of surgery |
| intraoperative peak airway pressure | during intraoperative ventilation |
Outcome results
None listed