Cancer, Solid Tumor, Adult
Conditions
Brief summary
Historically, cancer research has been limited by sample acquisition in late stage disease, often restricted to single sites of disease with limited parallel clinical data collection in terms of prior therapy exposure. The PEACE study is intended to facilitate tissue donation from multiple tumour sites in the post-mortem setting and enable future research using samples collected at post-mortem within different disciplines related to cancer research.
Interventions
OTHERTissue Harvest
Sponsors
Cancer Research UK
University College, London
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age 18 years or older * Confirmed diagnosis of any form of solid malignancy with metastatic disease (where the site of origin is known or unknown), with the exception of primary brain tumour in which there may not be evidence of metastatic disease * Oral and written informed consent from patient to enter the study and to undergo tumour harvesting after death or informed consent from a person in a qualifying relationship after the patient has died.
Exclusion criteria
* Medical or psychiatric condition that would preclude informed consent * History of intravenous drug abuse within the last 5 years * History of known high-risk infections (e.g. HIV/AIDS-positive, hepatitis B/C, tuberculosis and Creutzfeldt-Jacob disease).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perform 500 post mortems | 5 years |
Countries
United Kingdom
Contacts
Primary ContactAbby Sharp
Outcome results
None listed