Oral Tissue
Conditions
Keywords
Reflectance Confocal Microscopy, Normal Oral Tissue, 16-1652
Brief summary
The purpose of this study is to obtain images (pictures) of normal oral tissue, which occur inside the mouth, using a special camera. These pictures will be used in our research to evaluate a new technology that uses a laser and takes pictures of the microscopic structure of tissue. The technology is called reflectance confocal microscopy.
Interventions
DEVICEReflectance Confocal Microscopy (RCM) endoscope device
Sponsors
Memorial Sloan Kettering Cancer Center
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Healthy volunteers * Ability to sign informed consent * Age ≥ 18 years.
Exclusion criteria
* Inability to give informed consent. * Previously known oral disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| number of images with acceptable quality | 1 year | Each image will be scored either 1 (completely unacceptable), 2 (unacceptable), 3 (possibly acceptable), 4 (acceptable) or 5 (very acceptable) relative to a reference standard The reference standard for appearance of adequate sectioning, resolution and contrast and for detectability of nuclear and cellular features will be the appearance of images and image quality, which we are intimately familiar with, based on the past several years of experience with the existing RCM device for which images of oral mucosa have been well-characterized, well-correlated to histology, and thus are well-understood. |
Countries
United States
Outcome results
None listed