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Effects of Direct Laryngoscopic and Fiberoptic Intubation on Intraocular Pressure

Comparison of Effects of Direct Laryngoscopic and Fiberoptic Oral Endotracheal Intubation on Intraocular Pressure

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03003585
Enrollment
54
Registered
2016-12-28
Start date
2016-12-31
Completion date
2017-04-04
Last updated
2017-04-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraocular Pressure, Intubation Complication

Keywords

intraocular pressure, direct laryngoscopy, fiberoptic bronchoscopy

Brief summary

In this study, the investigators aimed to compare the effects of direct laryngoscopic and fiberoptic endotracheal intubation on intraocular pressure.

Detailed description

Material and Method: Total of 54 American Society of Anesthesiologist Grade 1-2, Mallampati score 1 or 2, age between 18 to 65 patient planned to undergo nonopthalmic surgery will be included to study. Patients with glaucoma, diabetes mellitus, cardiovascular and pulmonary diseases, American Society of Anesthesiologist Grade III and IV, body mass index more than 35, difficult intubation, undergo obstetrical surgery and propofol, fentanyl, rocuronium contraindicated will be excluded from the study. Patients will be divided randomly into 2 groups as direct laryngoscopic and fiberoptic intubation group. Patients will be preoxygenated with %100 O2 for 3 minutes then anesthesia will be induced using propofol 2 mg / kg, fentanyl 1 mcg/kg, and rocuronium 0,5 mg / kg in both groups. After 3 minutes mask ventilation, patients will be intubated (women with No:7-7,5, men with No:8-8,5 intubation tube). Systolic blood pressure, diastolic blood pressure, mean arterial pressure, peripheral oxygen saturation,perfusion index will be recorded and intraocular pressure measured by ophthalmologist by tonopen device will be recorded pre-induction (basal), after induction, 1,2,3,5 minutes after intubation, respectively. Period between handling of laryngoscope or fiberoptic device after termination of mask ventilation and obtain end tidal CO2 will be accepted as application time and recorded. Study will be terminated after 5th minute values taken.

Interventions

This device is used in endotracheal intubation and tonopen device for measuring of intraocular pressure. The investigators want to evaluate which one is better.

This device is used in endotracheal intubation and tonopen device for measuring of intraocular pressure. The investigators want to evaluate which one is better.

Sponsors

Inonu University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Investigator)

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* ASA (American Society of Anesthesiologist) Grade 1-2, * Mallampati score 1 or 2, * Age between 18 to 65 * Patient planned to undergo nonopthalmic surgery.

Exclusion criteria

* Patients with glaucoma, diabetes mellitus, cardiovascular and pulmonary diseases, ASA Grade III and IV, BMI more than 35, * Patients with difficult intubation, * Patients undergoing obstetrical surgery and propofol, fentanyl, rocuronium contraindicated.

Design outcomes

Primary

MeasureTime frame
Intraocular pressureFrom Beginning of Anesthesia induction to 5th minutes of intubation
Systolic blood pressureFrom Beginning of Anesthesia induction to 5th minutes of intubation
Heart rateFrom Beginning of Anesthesia induction to 5th minutes of intubation
Adverse eventswithin the first 24 hour after surgery

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026