Substance Dependence
Conditions
Keywords
cognitive bias modification, interpretation bias, suicidal ideation, depression
Brief summary
The purpose of this study is to determine whether computer bias modification for interpretation bias (CBM-I) is effective in the reduction of suicidal ideation in substance use disorders.
Detailed description
Eighty-eight adult inpatients completing residential treatment in the Addictions Services at the Centre for Addiction and Mental Health (CAMH) will be randomized to receive CBM-I daily for one week, adjunct to the residential psychosocial treatment or to an assessment-only control condition. Participants will complete clinical measures consisting of interviews and questionnaires measuring suicidal ideation, hopelessness, depression, negative affect, and interpretation biases before, during and after treatment.
Interventions
BEHAVIORALCognitive Bias Modification
Training paragraphs describe scenarios designed to be ambiguous at the outset and to resolve in a positive direction, with the intention of establishing a learning contingency between the ambiguity at the beginning of the scenario and the positive resolution that becomes clear towards the end of the statement.
Sponsors
American Foundation for Suicide Prevention
Centre for Addiction and Mental Health
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Exhibit moderate suicide risk or greater * Be enrolled in the Addictions Services inpatient program * Fluent in reading English * Capacity to give informed consent
Exclusion criteria
* A lifetime diagnosis of a psychotic or bipolar disorder * Significant neurological disorder or psychical illness likely to interfere with participation * Psychotropic medication changes within the past two weeks
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Columbia-Suicide Severity Rating Scale, Screen Version (C-SSRS) | Seven days | This scale quantifies the severity of suicidal ideation and behaviour. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Beck Hopelessness Scale (BHS) | Seven days | This questionnaire assesses thoughts and emotions associated with the future. |
| Beck Depression Inventory II (BDI-II) | Seven days | This questionnaire assesses severity of depressive symptoms and cognitions. |
| Positive and Negative Affect Schedule (PANAS) | Seven days | This questionnaire assesses current positive and negative mood |
| Scrambled Sentences Tests | Seven days | This computer test will be used as an implicit measure of negative interpretation bias. |
Countries
Canada
Outcome results
None listed