Postoperative Pain
Conditions
Brief summary
This is a retrospective chart review using TriHealth Electronic Privacy Identification Center (EPIC) and previously developed databases for TriHealth Institutional Review Board (IRB) approved research studies within the Division of Urogynecology and Reconstructive Pelvic Surgery to determine the predictors of postoperative pain specific to the urogynecologic patient population.
Detailed description
Postoperative pain remains the most important consideration for both patients and surgeons. Therefore, there has been much attention brought toward investigating predictive factors of postoperative pain. A systematic review of 48 eligible studies with 23,037 patients showed preexisting pain, anxiety, age, and type of surgery are the four most significant predictive factors for the intensity of postoperative pain. However, this paper evaluated all types of surgical approaches. More recently, a prospective observational study showed that preoperative State Trait Anxiety Inventory (STAI) and Numerical Rating Scales (NRS) for anxiety and pain expectations are independent predictors of pain and morphine consumption following abdominal hysterectomy. To date, little is known about the predictive factors of postoperative pain in the urogynecologic patient population. The purpose of this study is to determine the predictors of postoperative pain specific to the urogynecologic patient population. We aim to investigate the relationship between perioperative factors (such as demographics and medical history) and postoperative pain scores on postoperative day 1 with patients who have undergone urogynecologic surgery, specifically vaginal reconstruction for pelvic organ prolapse. This information would not only fill a gap in knowledge, but would also allow us to counsel our patients more accurately in regards to postoperative expectations. Furthermore, if we find any positive correlation between modifiable perioperative factors and postoperative pain scores, we may be able to minimize these effects in future surgical cases.
Interventions
None listed
Sponsors
TriHealth Inc.
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Participant in one of six research studies previously performed by the Division of Urogynecology and Pelvic Reconstructive Surgery (#13090, #13072, #12136, #12132, #10072, or #09001) * Postoperative pain scoring data complete and available * Vaginal reconstructive surgery as primary treatment * General anesthesia
Exclusion criteria
* Incomplete or unavailable postoperative pain scoring * Robotic sacrocolpopexy patients will be excluded
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Visual Analog Scale (VAS) Pain Score | postoperative day 1 (POD1) | VAS is a validated 100 millimeter scale with no pain as 0 mm and worst pain as 100 mm. Subjects drew a vertical line on the scale corresponding to their pain level. |
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| Reconstructive Surgery Eligible trials enrolled subjects undergoing vaginal reconstructive surgery for pelvic organ prolapse from 2009 to 2015. | 364 |
| Total | 364 |
Baseline characteristics
| Characteristic | Reconstructive Surgery |
|---|---|
| Age, Continuous | 59.44 years STANDARD_DEVIATION 11.42 |
| Race/Ethnicity, Customized African American | 9 Participants |
| Race/Ethnicity, Customized Asian | 2 Participants |
| Race/Ethnicity, Customized Caucasian | 351 Participants |
| Race/Ethnicity, Customized Missing | 1 Participants |
| Race/Ethnicity, Customized Other | 1 Participants |
| Region of Enrollment United States | 364 participants |
| Sex: Female, Male Female | 364 Participants |
| Sex: Female, Male Male | 0 Participants |
Adverse events
| Event type | EG000 affected / at risk |
|---|---|
| deaths Total, all-cause mortality | 0 / 364 |
| other Total, other adverse events | 0 / 364 |
| serious Total, serious adverse events | 0 / 364 |
Outcome results
Primary
Visual Analog Scale (VAS) Pain Score
VAS is a validated 100 millimeter scale with no pain as 0 mm and worst pain as 100 mm. Subjects drew a vertical line on the scale corresponding to their pain level.
Time frame: postoperative day 1 (POD1)
| Arm | Measure | Value (MEAN) | Dispersion |
|---|---|---|---|
| Reconstructive Surgery | Visual Analog Scale (VAS) Pain Score | 38.16 mm | Standard Deviation 24.89 |