Key Aspects of Medical Practice in Patients With Haemophilia A

Status

Withdrawn

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02996942

Acronym

KAPPA

Enrollment

Registered

2016-12-19

Start date

2012-07-31

Completion date

2017-12-31

Last updated

2018-12-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Joint Disease

Keywords

haemophilia, joint disease, quality of life

Brief summary

The KAPPa project has the aim to create an international database in which information about clinical features, therapeutic management, burden of illness and costs of severe and moderate haemophilia A patients from different countries and sites is collected. The aim of this project is to analyse the influence of such different characteristics on medical, psychosocial and economic outcomes in patients over the long-term.

Detailed description

1000 patients with hemophilia A will be enrolled using a webbased registry. Key quality factors that will be registered are : hemophilia joint Health score (HJHS), annual bleed rate, quality of Life (EQ5D), as well as dosing of replacement therapy.

Interventions

BIOLOGICALFactor VIII replacement

Patients receive their usual treatment

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

or forms. * severe haemophilia A (factor VIII\<1%) * moderate (factor VIII\<5%) * signed informed consent

Exclusion criteria

* Not fullfilling inclusion criteria

Design outcomes

Primary

Measure	Time frame	Description
Outcome of factor replacement treatment	3 years	Joint disase according to HJHS. Quality of Life. Health economic evalaution.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026