Effects of Danggui Buxue Tang on Blood Biochemical Parameters in Male Recreational Runners

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02996786

Enrollment

Registered

2016-12-19

Start date

2016-10-31

Completion date

2017-07-31

Last updated

2018-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fatigue, Hemolysis, Inflammation, Iron Deficiency, Oxidative Stress, Sports Anemia

Brief summary

The aim of this study is to examine the beneficial effects of Danggui Buxue Tang on blood biochemical parameters in male recreational runners.

Detailed description

1. Male recreational runners would be recruited by community websites or email. After completely introducing the study, the participants would be requested to sign informed consent. 2. The participants would perform maximal oxygen consumption test prior to the supplementation. The participants would be supplemented with either Danggui Buxue Tang or placebo for a week before performing the 13-km run. A total of 4 times blood collection (before supplementation, immediate after running, 1 day and 3 days after running) would be performed for evaluating the effect of Danggui Buxue Tang on blood biochemical parameters.

Interventions

DIETARY_SUPPLEMENTDanggui Buxue Tang

Danggui Buxue Tang purchased from Kaiser Pharmaceutical

OTHERPlacebo

Consisting of corn starch and carboxymethyl cellulose

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

MALE

Age

20 Years to 30 Years

Healthy volunteers

Yes

Inclusion criteria

* The participants should have the experience finishing 10-km run but without the experience of attending a marathon run.

Exclusion criteria

* Participants suffering from anemia (Hb \<13 g/dL), taking usual supplements, medication, alcohol or not feeling comfortable.

Design outcomes

Primary

Measure	Time frame	Description
Hematological parameters	Through study completion, an average of 1 year	Complete blood counts and serum haptoglobin and erythropoietin
Iron status	Through study completion, an average of 1 year	Serum iron, ferritin, transferrin and hepcidin
Oxidative stress	Through study completion, an average of 1 year	Thiobarbituric acid reactive substances, superoxide dismutase, catalase, and glutathione peroxidase
Inflammatory response	Through study completion, an average of 1 year	High-sensitivity c-reactive protein, Tumor necrosis factor-alpha, and interleukin-6

Secondary

Measure	Time frame	Description
Running time	Through study completion, an average of 1 year	The completion time for a 13-km run

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026