Giant Cell Tumor of the Extremities Treated With Surgery and/or Medical Treatment

Il Tumore a Cellule Giganti Delle estermità

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02996734

Acronym

GCTLIMBS

Enrollment

412

Registered

2016-12-19

Start date

2016-04-30

Completion date

2016-12-31

Last updated

2016-12-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Giant Cell Tumor of Bone

Keywords

bone tumors, giant cell tumor, treatment

Brief summary

The purpose of this project is to present the outcomes of patients with giant cell tumor of bone (GCTB) who were treated with surgery and/or medical treatment in a single institution.

Detailed description

The investigators retrospectively review patients treated for GCTB of the extremities between 1990 and 2013 in a single institution. We evaluate the recurrence free survival rate after surgical and medical treatment of patients with GCTB of the extremities to determine the influence of the surgical approach, denosumab therapy, local tumor presentation, and demographic factors on the risk of recurrence.

Interventions

PROCEDUREcurettage and resection

the investigators analyzed patients with giant cell tumor of bone who underwent curettage or resection with or without denosumab administration

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* giant cell tumors of the extremities

Exclusion criteria

* giant cell tumors of the spine and pelvis

Design outcomes

Primary

Measure	Time frame
local recurrence rate after surgical and medical treatment	within the first 36 months after surgery

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026