Embryonic Development, Fertilization in Vitro, Infertility
Conditions
Brief summary
The aim of this study is to examine the length of ovarian stimulation with the timing of trigger in an IVF cycle and its potential to impact patient outcomes.
Interventions
OTHERTiming of trigger
Sponsors
Fertility Laboratories Of Colorado
Colorado Center for Reproductive Medicine
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
26 Years to 44 Years
Healthy volunteers
Yes
Inclusion criteria
* Planning to move forward with an IVF cycle * Have met the requirements of being a patient at CCRM Colorado * AMA: 39-44 years old And/or * DOR: AMH \< 1 & FSH \>10 (age independent)
Exclusion criteria
* Contraindication for pregnancy * Have not fulfilled requirements for IVF cycle * Single gene couple or chromosomal rearrangement * Severe male factor or testicular surgical sperm removal (need sufficient sperm for ICSI) * One ovary * Uterine anomalies * Stage III or IV endometriosis * Explained recurrent miscarriage * PCO or PCOS * Using donor oocyte or gestational carrier
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Euploid Embryos: the percentage of euploid embryos produced as analyzed by comprehensive chromosomal screening, of total embryos tested | 4 weeks after egg retrieval |
Secondary
| Measure | Time frame |
|---|---|
| Egg maturation: the proportion of mature eggs of total number of eggs retrieved | 1 week after egg retrieval |
| Live birth outcomes: the incidence of pregnancy resulting in live birth following embryo transfer of embryos produced by this IVF cycle | 9 months after frozen embryo transfer |
Countries
United States
Outcome results
None listed