Protein Deficiency
Conditions
Keywords
PROTEIN SUPPLEMENTATION, NUTRITIONAL STATUS
Brief summary
The purposes of the study are: * To strictly ensure the appropriate level of protein and caloric provision in critical illness, according to the latest literature recommendation; * To determine if an association exists between protein intake and nitrogen balance in the context of a nutrition with appropriate protein provision based on the latest literature recommendations, rather than in a standard diet with a caloric target weight-based. Creatinine clearance will also be evaluated to determine if there is any harmful effect to the kidney secondary to an elevated BUN. * To determine if there is a difference in ICU mortality rate between the current nutrition standard and a hyperproteic nutrition protocol.
Interventions
Sponsors
Study design
Eligibility
Inclusion criteria
* Age \> 18 years * Receiving PN and/or EN nutrition * Indwelling urinary catheter * Mechanically ventilated patients
Exclusion criteria
* Age \< 18 years * Chronic renal or hepatic failure * Current or history (past 6 months) of GI bleeding * BMI \>30 kg/m2 o \<18 kg/m2 * Terminally ill patients * Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| nitrogen balance (gr) | change from baseline through study completion, an average of 15 days | (gr) |