Stroke, Acute
Conditions
Brief summary
The aim of this study is to address the usefulness of carotid duplex ultrasound as vascular imaging for selecting acute stroke patients for endovascular thrombectomy.
Interventions
PROCEDUREAfter detection of occluded vessels by vascular imaging using carotid duplex ultrasound, digital subtraction angiography is immediately performed before acute endovascular treatment.
When the ratio of the end diastolic velocity in the common carotid arteries is greater than 1.4 or the diastolic flow in the internal carotid artery is not detected by vascular imaging using carotid duplex ultrasound, digital subtraction angiography is immediately performed before acute endovascular treatment. If vessel occlusion is not detected by carotid duplex ultrasound, additional vascular imaging including MR angiography or CT angiography is considered.
Sponsors
Ryo Itabashi
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Endovascular treatment can be initiated within 6 hours of symptom onset. * ASPECTS of \>=6 is diagnosed by two or more stroke physicians. * The end diastolic velocity in the common carotid arteries or internal carotid artery is evaluated by carotid duplex ultrasound * NIHSS score of \>=6. * Age\>=18 years. * Written informed consent is obtained.
Exclusion criteria
* Pre-stroke modified Rankin Scale (mRS) score \>=2. * Difficulties to evaluate ASPECTS on initial CT. * Difficulties to groin puncture. * History of severe allergic reaction to contrast medium. * End stage renal disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| modified Rankin Scale | at 90 days after onset |
Countries
Japan
Outcome results
None listed