Chronic Obstructive Pulmonary Disease, Interstitial Lung Disease
Conditions
Brief summary
The LTRC will facilitate histopathological research of pulmonary diseases by collecting lung tissues from donors and preparing and distributing collections of tissue specimens to researchers within and outside the LTRC. Collections of specimens will be linked to individual clinical data appropriate to the particular disease. The primary goal of the LTRC is to identify participants with suspected lung cancer or metastatic disease who are willing to provide informed consent for research use of their specimens and data. Secondarily, the LTRC investigators intend to collect clinical data, limited exposure data, physiologic studies, and radiographic studies from these participants.
Interventions
PROCEDURELung biopsy/lobectomy
Lung biopsies and lobectomies are not experimental. Participants will undergo a lung biopsy or a lobectomy as part of standard of care.
Sponsors
National Heart, Lung, and Blood Institute (NHLBI)
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
21 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Adults ages 21 or older who are undergoing lung surgery for suspected malignancy or metastases.
Exclusion criteria
* Diagnosis of cystic fibrosis or pulmonary hypertension. * Any other condition that, in the judgment of the investigator, precludes participation. * Failure to obtain written consent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Clinical diagnosis | Two months following surgery | A final diagnosis of the participant's lung disease will be rendered by the clinical center PI. |
Countries
United States
Outcome results
None listed