Patients in Minimally Conscious State
Conditions
Brief summary
In this study，researchers will use personalized objects to assess patients' level of consciousness in chronic patients in minimally conscious state (MCS).
Detailed description
The Coma Recovery Scale-Revised (CRS-R) is an important tool for the assessment of behaviors in DOC.Clinical practice has shown that self-referential stimuli, such as the patient's own name and face, are more effective to elicit the patient's response than that of non-self-referential stimuli. The item Functional Object Use was assessed by using personalized objects (e.g., cigarette, paper) and non-personalized objects, which presented in a random order.The rest assessments were performed following the standard protocol of CRS-R. The differences between functional use of the two types of objects was analyzed by Chi-square test. Researchers expected to see some of the patients in MCS are re-diagnosed as EMCS with the using of personalized objects.
Interventions
BEHAVIORALPersonalized Objects
personalized objects are based on the observation or the reports from family
BEHAVIORALnon-personalized Objects
non-personalized objects are based on the suggestion in CRS-R,which are comb and cup
Sponsors
Hangzhou Normal University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
15 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* patients in minimally conscious state; * patients with stable condition; * each patient has athletic ability to some extent.
Exclusion criteria
* premorbid neurology antecedent; * patients in coma or vegetative state; * patients \< 1 months after the acute brain injury.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The frequency of behavioral response elicited by the stimuli suggested by CRS-R scale and the personalized stimuli they prefer | one week |
Outcome results
None listed