Gingival Recession
Conditions
Keywords
gingival graft, free gingival graft, coronally advanced flap, reduced keratinized gingiva
Brief summary
Twenty patients with gingival recession will be enrolled in this trial. Gingival recession will be treated in one side by applying Mucograft® with coronally advanced flap (CAF) while on the opposite side a connective tissue graft (from the palate) will be applied with a CAF. Patients will be followed for 3 and 6 months by measuring the clinical indexes and statistical analyses will be performed to compare the results and to assess the success of Mucograft®.
Detailed description
Many surgical techniques have used to treat gingival recession such aas repositioned flaps, autologous soft tissue grafts (connective tissue graft or free gingival grafts) or allografts like acellular dermal which can be used as substitutes for palatal donor tissue. Mucograft® (3D collagen matrix) is also an allograft from porcine origin and is designed for soft tissue regeneration and considered the ideal solution to autogenous soft tissue grafts and it provides an ideal matrix for blood vessel and soft tissue ingrowth.
Interventions
PROCEDUREMucograft
This method of grafting will be used to treat the gingival recession using coronally advanced flaps.
PROCEDUREConnective Tissue Graft
This will be used in the traditional manner to correct gingival recession
Sponsors
Damascus University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* Presence of Type I or II (Miller Classification) of gingival recession
Exclusion criteria
* Smoking * Pregnancy or lactating * Presence of any systematic diseases can affect the periodontal surgery. * Subjects with significant moderate to severe periodontal disease. * Patients under orthodontic treatment * Presence of restorative materials (e.g. crown) * Effectiveness of frenum * Subjects have failed to maintain good plaque control. * Subjects having previous surgical treatment for covering the recession in the chosen area.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in the Clinical Attachment Level Index | Measurements will be done at :(1) one hour before applying the graft, (2) at three months exactly post-operatively and (3) at six months exactly post-operatively | Clinical Attachment Level is dependent on measuring the pocket depth as well as the amount of gingival recession using specific tools. The measurement is going to be recorded in millimeters. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in Probing Depth | Measurements will be done at :(1) one hour before applying the graft, (2) at three months exactly post-operatively and (3) at six months exactly post-operatively | Probing depth is going to be measuring using a specific tool (UNC-15 probe). |
| Change in Gingival Recession | Measurements will be done at :(1) one hour before applying the graft, (2) at three months exactly post-operatively and (3) at six months exactly post-operatively | Gingival recession is measured from the cemento-enamel junction to the gingival margin of the recessed tissues. |
| Change in Gingival Biotype | Measurements will be done at :(1) one hour before applying the graft, (2) at three months exactly post-operatively and (3) at six months exactly post-operatively | Gingival biotype is assessed by an endodontic file which used to determine the thickness of the gingival tissues (i.e. thick or thin). |
| Change in Root Coverage Index | Measurements will be done at :(1) one hour before applying the graft, (2) at three months exactly post-operatively and (3) at six months exactly post-operatively | The amount of root exposure will be measured and compared to the total length of the root |
| Change in Resistance to Muscular Pull | Measurements will be done at :(1) one hour before applying the graft, (2) at three months exactly post-operatively and (3) at six months exactly post-operatively | The cheeks or lips are going to be retracted by hand or by a mirror in order to see the movement of the free gingival tissues. The movement will be esitmated in millimeters. |
| Change in Color Match Index | Measurements will be done at :(1) one hour before applying the graft, (2) at three months exactly post-operatively and (3) at six months exactly post-operatively | — |
| Shrinkage index at three months | Measurements will be done at two time points to calculate the amount of shrinkage :(1) at one hour before applying the graft, (2) at three months exactly post-operatively. | — |
| Shrinkage index at six months | Measurements will be done at two time points to calculate the amount of shrinkage :(1) at one hour before applying the graft, (2) at six months exactly post-operatively. | — |
Countries
Syria
Outcome results
None listed