Acceptability and Feasibility of Medical Abortion in Singapore

Acceptability and Feasibility of Medical Abortion in Singapore: A Study of 800 μg Buccal Misoprostol Following 200 mg Mifepristone for Abortion Through 70 Days Gestation

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02985229

Enrollment

130

Registered

2016-12-07

Start date

2016-10-31

Completion date

2017-07-31

Last updated

2018-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Medical Abortion

Brief summary

To test the hypothesis that a regimen of 200 mg oral mifepristone, with the option of home administration, followed by 800 μg buccal misoprostol 24 hours later for abortion through 70 days LMP will be feasible and acceptable in Singapore.

Interventions

DRUGMifepristone

The option of home or clinic administration of 200 mg oral mifepristone

DRUGMisoprostol

800 μg buccal misoprostol through 70 days LMP following administration of mifepristone

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

21 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Have an intrauterine pregnancy consistent wit gestational age ≤ 70 days * Be 21 years of age or over * Be willing and able to sign consent forms * Be eligible for abortion according to current hospital guidelines * Be able to return to the clinic and able to contact study staff or emergency medical services if needed * Be willing to provide an address, email and/or telephone number for purposes of follow-up * Agree to comply with the study procedures and visit schedule

Exclusion criteria

* confirmed or suspected ectopic pregnancy or undiagnosed adnexal mass * chronic renal failure * concurrent long-term corticosteroid therapy * history of inherited porphyrias * IUD in place (must be removed after mifepristone is administered).

Design outcomes

Primary

Measure	Time frame	Description
Rate of successful abortion	7-10 days after mifepristone administration	Proportion of abortions that are complete without surgical intervention

Secondary

Measure	Time frame	Description
Satisfaction with the medical abortion method	7-10 days after mifepristone administration	Proportion of women who are satisfied with the medical abortion method
Preferred location of mifepristone administration	The day of enrollment	Proportion of women who select home use of mifepristone

Countries

Singapore

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026