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Objective Physical Activity Assesment in Postmenopausal Women

The Use of Lactate Thresholds to Individualize Accelerometer Cut-points and Objectively Assess Physical Activity Levels in Postmenopausal Women

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02984553
Enrollment
80
Registered
2016-12-07
Start date
2015-11-30
Completion date
2017-07-31
Last updated
2016-12-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Prevention

Keywords

accelerometry, aerobic fitness, metabolic thresholds, moderate to vigorous physical activity

Brief summary

The purpose of this study is to accurately assess weekly physical activity levels of postmenopausal women using lactate thresholds to individualize the accelerometer cut-points.

Detailed description

This observational study aims to accurately assess weekly physical activity levels of postmenopausal women using lactate thresholds to individualize the accelerometer cut-points. Postmenopausal women will be recruited from local advertisements in public health centers. Each woman will perfom on different days a progressive discontinuous submaximal walking-running test and several constant speed tests wearing an accelerometer to identify the individual lactate threshold (LT), the maximal lactate steady state (MLSS) and the corresponding accelerometer activity counts/min (cpm). Participants then will wear an actigraph accelerometer (wGT3X-BT) for seven days. Linear regression equations will be developed for each participant to determine accelerometer activity counts for each intensity level: 1) sedentary behaviour (\<200 cpm), 2) light intensity (200 cpm to activity counts at LT), 3) moderate intensity (activity counts between LT and MLSS) and 4) vigorous intensity (activity counts \>MLSS). Physical activity levels will be measured using both, individualized approach and Sasaki, Jonh and Freedson´s (2011) absolute cut-points obtained through walking and running activities eliciting 3-6 MET intensities (2689-6166 cpm), considering it a moderate effort.

Interventions

None listed

Sponsors

University of the Basque Country (UPV/EHU)
CollaboratorOTHER
Centro de Estudios, Investigación y Medicina del Deporte
Lead SponsorOTHER_GOV

Study design

Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
FEMALE
Age
50 Years to 70 Years
Healthy volunteers
Yes

Inclusion criteria

* Age between 50 and 70 years * Surgical or natural menopause (no menstrual periods during at least the last 6 months)

Exclusion criteria

* Body mass index less than 39kg/m2 (obesity class III) * Osteoporosis * Presence of low-trauma fractures or severe arthrosis at hip, knees or feet * Functional limitation to walk fast or altered gait patters and instability * Presence of any chronic disesase that would impair the cardiovascular (e.g. myocardial infarction, stroke, chronic heart failure), musculoskeletal (osteoporosis, low-trauma fractures) and respiratory systems (COPD) or any disease or medication known to affect bone metabolism (glucocorticoids)

Design outcomes

Primary

MeasureTime frameDescription
Time spent in moderate-to-vigorous physical activities1 weekThe time spent in moderate-to-vigorous physical activities during a week (The participants have to wear an accelerometer attatched at the hip on an elastic belt for a period of 7 days)

Secondary

MeasureTime frameDescription
accelerometer intensity cut-pointsan average of 1 monthaccelerometer activity counts corresponding to each woman´s lactate thresholds will determine each intensity level (These thresholds are determined on the walking-running tests performed on different days with a minimum of one week in between. These tests are independent, they are performed at constant speed during 20min to determine the highest speed at which the lactate concentration remains in a steady state between the minute 10 and 20 of the test)
Number of vertical acceleration peaks during the day1 weekraw acceleration data will be measured to describe daily exposure to potentially osteogenic vertical impacts (The participants have to wear an accelerometer attatched at the hip on an elastic belt for a period of 7 days)
aerobic fitnessan average of 1 monthdetermination of the speeds corresponding to the lactate thresolds during the walking-running test

Other

MeasureTime frameDescription
Maximum Strength1 dayhand grip, leg and bench press maximum lifted weight (kg)
Heart rate variabilityan average of 1 monththe heart rate variability response during the walking-running tests and during the weekly physical activity assessment

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026