Healthy
Conditions
Brief summary
The present study will seek to quantify the muscle protein synthetic response to mycoprotein feeding, comparing it to milk protein as a gold standard and heavily researched positive control
Interventions
OTHERMycoprotein beverage
Mycoprotein protein beverage
OTHERMilk protein beverage
Milk protein beverage
Sponsors
University of Exeter
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
MALE
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
• BMI between 18 and 30 -
Exclusion criteria
* Any diagnosed metabolic impairment (e.g. type 1 or 2 Diabetes) * Any diagnosed cardiovascular disease or hypertension. * Elevated blood pressure at the time of screening (e.g. blood pressure of ≥140/90mmHg). * Chronic use of any prescribed or over the counter pharmaceuticals. * A personal or family history of epilepsy, seizures or schizophrenia. * Anyone with previous motor disorders. * An allergy to mycoprotein / Quorn, penicillin, or milk.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Muscle fractional synthetic rate (muscle protein synthesis) | 7.5 hours |
Secondary
| Measure | Time frame |
|---|---|
| Plasma amino acid concentration | 7.5 hours |
| Serum insulin concentration | 7.5 hours |
| Molecular markers of muscle anabolism | 7.5 hours |
Countries
United Kingdom
Outcome results
None listed