Body Composition Changes During Stem Cell Transplantation: The Case Of Lymphoma Patients

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02983643

Enrollment

105

Registered

2016-12-06

Start date

2016-01-31

Completion date

2018-03-31

Last updated

2017-05-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hematopoietic Stem Cell Transplantation, Malnutrition, Metabolic Syndrome

Keywords

Skeletal Muscle Index, Visceral Adipose Tissue, Metabolic Syndrome

Brief summary

Skeletal Muscle Index (SMI) and Visceral Adipose Ratio (VAR) assess body composition changes and disclose malnutrition risk effectively. The aims of the study are to assess prevalence of malnutrition in patients planned for SCT, to characterize changes in body composition (SMI, total adipose tissue and VAR) that occur in the peri transplantation phase, and to identify Waist Circumference (WC) cut off points associated with the metabolic syndrome (MetSyn) in patients with B and T cell Lymphoma.

Detailed description

This study is a retrospective cohort study of patients having B and T cell lymphoma, who underwent SCT in the Bone Marrow Transplantation (BMT) unit at AUBMC. Consecutive patients having B and T lymphoma who underwent SCT at AUBMC will be identified by the research team and will be included as per the below inclusion and exclusion criteria. Starting from June 2016, patients who meet the inclusion criteria will be included in the study up until June 2006. The radiologist will access the AUBMC PACS system to review PET/CT scans of the identified patients. SMI, visceral, subcutaneous and intramuscular adipose tissues will be established by assessing at the level of L3.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

16 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Age\>16 years * Patients having B and T cell lymphoma who have undergone SCT at AUBMC

Exclusion criteria

* Patients with a missing pre-SCT PET/ CT scan * Patients with 2 missing post SCT PET / CT scan

Design outcomes

Primary

Measure	Time frame
Sarcopenia Prevalence	3 months post Stem Cell Transplantation
Skeletal Muscle Index Changes	3 months post Stem Cell Transplantation

Countries

Lebanon

Contacts

Primary ContactJean El Cheikh, MD

je46@aub.edu.lb9611350000

Backup ContactJana Jabbour, LD, MPH

jj13@aub.edu.lb9611759668

Outcome results