Hepatitis C Infection in World Trade Center Responders

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02982993

Enrollment

3906

Registered

2016-12-06

Start date

2016-12-31

Completion date

2018-07-12

Last updated

2019-02-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatitis C Infection

Keywords

hepatitis C virus, linkage-to-care, World Trade Center Health Program cohort, Baby Boomer, risk factors for hepatitis C virus infection

Brief summary

This study provides Hepatitis C virus screening to the members of the World Trade Center Health Program followed at the Icahn School of Medicine at Mount Sinai born during 1945-1965, and linkage to care for those found infected. The study will also determine if exposure to human remains, blood and/or bodily fluids during the World Trade Center Health Program activities are associated with Hepatitis C virus infection. These findings would be relevant to the larger United States population, especially to persons born during 1945-1965 who are at high risk of Hepatitis C virus infection.

Detailed description

The purpose of the project is to determine if the World Trade Center Health Program cohort is at an increased risk of Hepatitis C virus infection, determine if human exposure to human remains, blood and/or body fluids during the World Trade Center recovery activities is associated with increased risk of Hepatitis C virus infection, and to determine if referral to a co-located site for Hepatitis C virus care is associated with improved linkage to Hepatitis C virus care in the members of the World Trade Center Health Program born during 1945 through 1965.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

51 Years to 72 Years

Healthy volunteers

Yes

Inclusion criteria

* Member of the World Trade Center Health Program at the Icahn School of Medicine at Mount Sinai * Born during 1945-1965

Exclusion criteria

* None

Design outcomes

Primary

Measure	Time frame	Description
Prevalence of Hepatitis C virus infection	2 years	The investigator will measure the prevalence of Hepatitis C virus infection in 3900 World Trade Center Health program members to test the hypothesis that World Trade Center Health program members have an increased risk of Hepatitis C virus infection.

Secondary

Measure	Time frame	Description
Correlation between the exposure to human remains, blood and/or bodily fluids to hepatitis C virus infection.	2 years	The investigator will test the measure of association between exposure to human remains, blood and / or bodily fluids and risk of hepatitis C virus infection, while adjusting for type of activity during work at World Trade Center site and use of personal protective equipment.

Countries

United States

Outcome results