Type2 Diabetes
Conditions
Brief summary
Large glucose excursions at breakfast are prevalent in type 2 diabetes and can contribute to sustained hyperglycaemia across the day. Lowering consumption of dietary carbohydrate is known to reduce post-meal glucose excursions but it is unknown whether lowering the carbohydrate at breakfast only will impact subsequent post meal glucose excursions throughout the day. The aim of this study is to examine, under free living conditions and using typical dietary patterns, whether eating a breakfast low in carbohydrate can lower daily post-meal glycemia when compared to consuming a low-fat breakfast (per the current diabetes guidelines).
Interventions
BEHAVIORALLow Carbohydrate Breakfast
A low carbohydrate breakfast containing \<10% carbohydrate, \ 75% fat, and 15% protein. Matched for calories to the active comparator arm.
BEHAVIORALGuidelines Breakfast
A low fat breakfast containing \ 55% carbohydrate, \<30% fat, and 15% protein. Matched for calories to the experimental arm.
Sponsors
University of British Columbia
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
30 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Physician-diagnosed Type 2 Diabetes (\>6 months)
Exclusion criteria
* Exogenous Insulin * A1c \> 9% * Cardiovascular, liver, or renal other disease * Breakfast and meal skippers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incremental area under the glucose curve (continuous glucose monitor) | 24 hour (one day) |
Secondary
| Measure | Time frame |
|---|---|
| Mean Blod Glucose (continuous glucose monitor) | 24 hours (one day) |
Other
| Measure | Time frame |
|---|---|
| Glycemic Variability (continuous glucose monitor) | 24 hours (one day) |
| Satiety VAS 100 | Before and after meals (one day) |
Countries
Canada
Outcome results
None listed