Patients Requiring Endotracheal Intubation and Invasive Mechanical Ventilation
Conditions
Brief summary
The main purpose of the present study was to explore the weaning failure rate from invasive mechanical ventilation and to identify risk factors of weaning failure.
Interventions
DEVICEInvasive mechanical ventilation
Invasive ventilation was performed to all eligible patients. When patients met predefined criteria, spontaneous breathing trial was performed. Given spontaneous breathing trial passed, patients were extubated; on the contrary, patients would continue to receive invasive ventilation. If patients had respiratory failure after extubation, reintubation and invasive ventilation were necessary.
Sponsors
Beijing Chao Yang Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Requiring endotracheal intubation and invasive mechanical ventilation
Exclusion criteria
* Duration of invasive mechanical ventilation \< 48 hours； * Presence of tracheostomy； * Presence of upper airway obstruction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weaning failure rate | 3.5 years |
| Spontaneous breathing trial failure rate | 3.5 years |
| Extubation failure rate | 3.5 years |
Secondary
| Measure | Time frame |
|---|---|
| ICU mortality | 3.5 years |
| Hospital length of stay | 3.5 years |
| Hospital mortality | 3.5 years |
| ICU length of stay | 3.5 years |
Countries
China
Contacts
Primary ContactZujin Luo, MD
Outcome results
None listed