Healthy
Conditions
Brief summary
The present study will assess the effect of the type and timing of protein ingestion 6 days prior to, and 7 days following eccentric exercise on the time course of 1) the recovery of muscle function, 2) the recovery of perceived muscle soreness, 3) muscle metabolism.
Interventions
DIETARY_SUPPLEMENTPost exercise protein-polyphenol supplement
Participants will ingest a post exercise protein-polyphenol supplement. This will begin 6 days before eccentric exercise and will end 6 days after eccentric exercise.
DIETARY_SUPPLEMENTPost exercise placebo supplement
Participants will ingest an isocaloric placebo supplement after exercise. This will begin 6 days before eccentric exercise and will end 6 days after eccentric exercise.
DIETARY_SUPPLEMENTPre bed protein-polyphenol supplement
Participants will ingest a protein-polyphenol supplement before bed. This will begin 6 days before eccentric exercise and will end 6 days after eccentric exercise.
DIETARY_SUPPLEMENTPre bed placebo supplement
Participants will ingest an isocaloric placebo supplement before bed. This will begin 6 days before eccentric exercise and will end 6 days after eccentric exercise.
Sponsors
University of Exeter
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* Men and women who are generally healthy and recreationally active
Exclusion criteria
* Active cardiovascular disease or hypertension * Diagnosed metabolic impairment * Use of nutritional supplements * Use of anti-inflammatory medications * Habitual dietary protein intake of \<0.8g/kg/day * Musculoskeletal disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Isokinetic force production of the knee extensor muscles | 14 days |
Secondary
| Measure | Time frame |
|---|---|
| Muscle protein synthesis | 14 days |
| Thigh volume | 14 days |
| Perceived muscle soreness | 14 days |
| Isometric force production of the knee extensor muscles | 14 days |
Countries
United Kingdom
Outcome results
None listed