Acid-Base Imbalance, Hypercapnia, Obesity Hypoventilation Syndrome, Obstructive Sleep Apnea, Post-Op Complication
Conditions
Keywords
Obstructive Sleep Apnea, Obesity Hypoventilation Syndrome, Hypercapnia, Post-Op Complication, Acid-Base Imbalance
Brief summary
Obstructive sleep apnea (OSA) and Obesity-Hypoventilation Syndrome (OHS) are common conditions in obesity, which may influence the prognosis in patients undergoing surgery. There is a need for simple screening tools to identify such patients at high risk. The current multicenter observational study aims to investigate occurrence of OSA and OHS in obese individuals undergoing elective abdominal surgery and further address its impact on perioperative and postoperative complications.
Detailed description
Obstructive sleep apnea (OSA) and Obesity-Hypoventilation Syndrome (OHS) are common conditions in obesity, which may influence the prognosis in patients undergoing surgery. There is a need for simple screening tools to identify such patients at high risk. The current multicenter observational study aims to investigate occurrence of OSA and OHS in obese individuals undergoing elective abdominal surgery by using questionnaires (STOPBANG questionnaire, Berlin Questionnaire, and Epworth Sleepiness Scale) and arterial blood gases. Perioperative and 72-h postoperative complications will be documented.
Interventions
None listed
Sponsors
Elazig Education and Research Hospital
Mustafa Kemal University
Aydin Adnan Menderes University
TC Erciyes University
Sisli Hamidiye Etfal Training and Research Hospital
Haydarpasa Numune Training and Research Hospital
Fatih Sultan Mehmet Training and Research Hospital
Konya Meram State Hospital
Ankara City Hospital Bilkent
Adana Numune Training and Research Hospital
Tepecik Training and Research Hospital
Sakarya University
Ankara University
Kahramanmaras Sutcu Imam University
Trakya University
Karadeniz Technical University
Dr. Lutfi Kirdar Kartal Training and Research Hospital
Turkiye Yuksek Ihtisas Education and Research Hospital
Ufuk University
Kasımpasa Training and Research Hospital
Nevsehir Public Hospital
Hitit University
Bulent Ecevit University
Medipol University
Marmara University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Patients undergoing elective abdominal surgery * Body-Mass-Index \>=30 kg/m2 * Ability to read and speak * Signed informed consent.
Exclusion criteria
* Use of diuretics * Use of theophylline * Use of respiratory depressing drugs * Severe lung disease (FEV1/FVC\<%50) * Severe hearth failure (EF\<%35) * Central nervous system or muscle disease * Untreated hypothyroidism * Renal failure (GFR\<50) * Total parenteral nutrition more than 72 hours * Hypokalemia * Hyponatremia * Hypomagnesemia * Hypoalbuminemia * Known sleep apnea or obesity hypoventilation syndrome * Blood transfusion from blood bank within 72 hours prior to surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative complications | 72 hours |
Countries
Turkey (Türkiye)
Contacts
Primary ContactIsmail Cinel, Prof Dr
Backup ContactYuksel Peker, Prof Dr
Outcome results
None listed