Excessive Worry
Conditions
Keywords
Excessive worry, Worry, Adolescents, Intolerance of uncertainty
Brief summary
This case series aims to test the feasibility and acceptability of streamlined cognitive behavioral therapy (CBT) for adolescents with excessive worry. The treatment protocol focuses on reducing intolerance of uncertainty and the hypothesis is that this will help reduce worry.
Detailed description
This pilot study aims to test a new form of Cognitive Behavioral Therapy for adolescents with excessive worry. The investigators will include 12 participants with excessive worry and test the treatment which focuses on reducing intolerance of uncertainty (IU) in order to reduce worry. Participants will be randomized to either one, two or three weeks of weekly baseline measurements prior to starting treatment, and will thus work as their on controls in this case series design. Primary outcome measures will be collected at 12 weeks after treatment start. Participants will be followed up at three months after treatment.
Interventions
BEHAVIORALCognitive behavioral therapy
CBT focused on reducing intolerance of uncertainty
Sponsors
Region Stockholm
Karolinska Institutet
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
13 Years to 17 Years
Healthy volunteers
No
Inclusion criteria
* A score on PSWQ-C of at least 22 * Age between 13 and 17 years * Ability to read and write in Swedish * A parent or caregiver that is able to co-participate in the treatment * Participants on psychotropic medication must have been on a stable dose for the last 6 weeks prior to baseline assessment
Exclusion criteria
* Diagnosis of autism spectrum disorder, psychosis, bipolar disorder or severe eating disorder * Present risk of suicide * Ongoing substance dependence * Occurrence of domestic violence * Completed CBT for any anxiety disorder within the last 6 months (defined as at least 5 sessions of CBT including in vivo exposure sessions)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Penn State Worry Questionnaire for Children (PSWQ-C) | At 12 weeks after treatment starts | Child and parent version |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Brief Intolerance of Uncertainty Scale (Brief IUS) | Baseline, weekly during treatment, 12 weeks after treatment starts, and three months after treatment has ended | Self rated tolerance to treatment |
| Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-KID) | Baseline, 12 weeks after start of treatment and three month after treatment has ended. | Diagnostic interview |
| Clinical Global Impression - Severity (CGI-S) | Baseline, 12 weeks after start of treatment and three month after treatment has ended. | Clinician rated severity of symptoms |
| Clinical Global Impression - Improvement (CGI-I) | At 12 weeks after start of treatment and three month after treatment has ended. | Clinician rated improvement after treatment |
| Children's Global Assessment Scale (CGAS) | Baseline, 12 weeks after start of treatment and three month after treatment has ended. | Clinician rated global functioning |
| Brief Why Worry-II (Brief WW2) | Baseline, weekly during treatment, 12 weeks after treatment starts, and three months after treatment has ended | Self rated positive assumptions of worry |
| Negative Problem Orientation Questionnaire (NPOQ) | Baseline, weekly during treatment, 12 weeks after treatment starts, and three months after treatment has ended | Self rated negative problem orientation |
| Revised Children´s Anxiety and Depression Scale (RCADS-C) | Baseline, 12 weeks after start of treatment and three month after treatment has ended. | Child and parent version. |
| Education, Work and Social Adjustment Scale (EWSAS) | Baseline, 12 weeks after start of treatment and three month after treatment has ended. | Child and parent version. |
| Brief Cognitive Avoidance Questionnaire (Brief CAQ) | Baseline, weekly during treatment, 12 weeks after treatment starts, and three months after treatment has ended | Self rated cognitive avoidance |
Countries
Sweden
Outcome results
None listed