The Impact of Distraction on Adenoma Detection Rate

The Impact of Distraction on Adenoma Detection Rate in Patients Undergoing Colonoscopy With Air Insufflation, Water Immersion and Water Exchange

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02978664

Enrollment

500

Registered

2016-12-01

Start date

2014-10-31

Completion date

2016-07-31

Last updated

2016-12-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adenoma

Keywords

colonoscopy, water exchange, adenoma detection rate, distraction

Brief summary

The investigators will review video-recordings of three randomized, controlled trials (NCT01535326, 01699399, and 01894191) comparing air insufflation, water immersion and water exchange during colonoscopy. These studies were all conducted at Buddhist Dalin Tzu Chi Hospital.

Detailed description

The investigators will review video-recordings of three randomized controlled trials (NCT01535326, 01699399, and 01894191) comparing air insufflation, water immersion and water exchange. These studies were conducted at Buddhist Dalin Tzu Chi Hospital. Permission will be obtained from the local Institutional Review Board (IRB) to review, analyze and report de-identified findings. Two experienced endoscopists (YHH and CWT) performed all the recorded colonoscopies. Recordings will be selected for review if they are complete examinations; include clear identification of the appendiceal orifice and/or the ileocecal valve, indicating arrival at the cecum; available in the appropriate format for video editing; and contain no patient or endoscopist identifiers. Patients with incomplete recordings and a history of bowel resection will be excluded from analysis. The included video recordings will be edited to remove the insertion phase to blind the study reviewer to the insertion techniques. One blinded reviewer uninvolved in the performance of the colonoscopies will be in charge of evaluating the selected videos, using the criteria described by Yung et al

Interventions

PROCEDUREAir insufflation

Air insufflation during colonoscopy including insertion phase

PROCEDUREwater immersion

Water will infused during insertion phase and removed during withdrawal phase of colonoscopy.

PROCEDUREWater exchange

Water will infused and removed during insertion phase of colonoscopy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

20 Years to 80 Years

Healthy volunteers

Inclusion criteria

* if they are complete examinations; include clear identification of the appendiceal orifice and/or the ileocecal valve, indicating arrival at the cecum; available in the appropriate format for video editing; and contain no patient or endoscopist identifiers.

Exclusion criteria

* Patients with incomplete recordings and a history of bowel resection will be excluded from analysis.

Design outcomes

Primary

Measure	Time frame
adenoma detection rate	one week after colonoscopy

Secondary

Measure	Time frame	Description
Distraction score	Immediate after video reviewing	—
Withdrawal technique as specified by Lee RH (citation 1)	immediate after video reviewing	adequacy of distention (0-5), fold examination (0-5) and cleaning (0-5) for each colonic segment
Bowel preparation score	immediate after video reviewing	Boston bowel preparation score

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026